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Merck
CN

BP886

Cyclobenzaprine hydrochloride

British Pharmacopoeia (BP) Reference Standard

Synonym(s):

5-(3-Dimethylaminopropylidene)dibenzo[a,e]cycloheptatriene hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C20H21N · HCl
CAS Number:
6202-23-9
Molecular Weight:
311.85
UNSPSC Code:
41116107
NACRES:
NA.24
MDL number:
MFCD00079039

Key Documents

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Product Name

Cyclobenzaprine hydrochloride, British Pharmacopoeia (BP) Reference Standard

InChI

1S/C20H21N.ClH/c1-21(2)15-7-12-20-18-10-5-3-8-16(18)13-14-17-9-4-6-11-19(17)20;/h3-6,8-14H,7,15H2,1-2H3;1H

SMILES string

Cl.CN(C)CC\C=C1\c2ccccc2C=Cc3ccccc13

InChI key

VXEAYBOGHINOKW-UHFFFAOYSA-N

grade

pharmaceutical primary standard

API family

cyclobenzaprine

form

solid

shelf life

limited shelf life, expiry date on the label

manufacturer/tradename

BP

application(s)

pharmaceutical
pharmaceutical small molecule

format

neat

storage temp.

2-8°C

Gene Information

human ... HTR2A(3356), HTR2C(3358)

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Related Categories

Application

Cyclobenzaprine hydrochloride BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:
  • Methadone Tablets
  • Methadone Injection
  • Methadone Oral Solution (1 mg per mL)
  • Methadone Concentrate for Oral Solution
  • Amitriptyline Oral Solution
  • Amitriptyline Tablets

    • Biochem/physiol Actions

    Skeletal muscle relaxant; 5-HT2 serotonin receptor antagonist.
    Skeletal muscle relaxant; reduces muscle spasm by depression of brainstem neurons; 5-HT2 serotonin receptor antagonist.

    General description

    This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

    Other Notes

    Sales restrictions may apply.
    Learn how British Pharmacopoeia (BP) sets the standard by offering quality British Pharmacopoeia Chemical Reference Substances (BPCRS).

    Packaging

    Unit quantity: 25 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

    pictograms

    Skull and crossbones
    GHS06

    signalword

    Danger

    Hazard Classifications

    Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation

    Storage Class

    6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

    wgk

    WGK 3

    flash_point_f

    Not applicable

    flash_point_c

    Not applicable

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