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BP1175

Fluconazole impurity standard

British Pharmacopoeia (BP) Reference Standard

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Synonym(s):
Fluconazole, 2-(2,4-Difluorophenyl)-1,3-bis(1H-1,2,4-triazol-1-yl)propan-2-ol
Empirical Formula (Hill Notation):
C13H12F2N6O
CAS Number:
86386-73-4
Molecular Weight:
306.27
MDL number:
MFCD00274549
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

fluconazole

form

solid

shelf life

limited shelf life, expiry date on the label

manufacturer/tradename

BP

application(s)

pharmaceutical
pharmaceutical small molecule

format

mixture

storage temp.

2-8°C

SMILES string

FC1=CC(F)=C(C(CN2N=CN=C2)(O)CN3N=CN=C3)C=C1

InChI

1S/C13H12F2N6O/c14-10-1-2-11(12(15)3-10)13(22,4-20-8-16-6-18-20)5-21-9-17-7-19-21/h1-3,6-9,22H,4-5H2

InChI key

RFHAOTPXVQNOHP-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Fluconazole impurity standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:
  • Fluconazole Oral Suspension
  • Fluconazole Capsules
  • Fluconazole Infusion

    • Biochem/physiol Actions

    Fluconazole is an antifungal agent. It is highly selective inhibitor of fungal cytochrome P-450 sterol C-14 α-demethyllation. Fluconazole is a potent inhibitor of CYP2C9. Fluconazole interferes with fungal ergosterol synthesis and downregulates the metallothionein gene.

    Packaging

    Unit quantity: 50 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

    Other Notes

    Sales restrictions may apply.

    related product

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    Fluconazole, Pharmaceutical Secondary Standard; Certified Reference Material

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    Y0000557

    Fluconazole, European Pharmacopoeia (EP) Reference Standard

    Y0000558

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    Y0000574

    Fluconazole impurity C, European Pharmacopoeia (EP) Reference Standard

    Y0000573

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    1271733

    Fluconazole Related Compound C, United States Pharmacopeia (USP) Reference Standard

    1271722

    Fluconazole Related Compound B, United States Pharmacopeia (USP) Reference Standard

    1271711

    Fluconazole Related Compound A, United States Pharmacopeia (USP) Reference Standard

    PHR1651

    Fluconazole Related Compound A, Pharmaceutical Secondary Standard; Certified Reference Material

    PHR1826

    Fluconazole Related Compound C, Pharmaceutical Secondary Standard; Certified Reference Material

    PHR1862

    Fluconazole Related Compound B, Pharmaceutical Secondary Standard; Certified Reference Material

    PHR2037

    Fluconazole Impurity H, Pharmaceutical Secondary Standard; Certified Reference Material

    BP1174

    Fluconazole, British Pharmacopoeia (BP) Reference Standard

    PHR2048

    Fluconazole Impurity G, Pharmaceutical Secondary Standard; Certified Reference Material

    PHR2046

    Fluconazole Impurity E, Pharmaceutical Secondary Standard; Certified Reference Material

    PHR1900

    Fluconazole Impurity A, Pharmaceutical Secondary Standard; Certified Reference Material

    PHR9026

    1,2,4-Triazole, reference material

    PHR9031

    2-(2,4-Difluorophenyl)-1,2,3-propanetriol, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

    Pictograms

    Health hazardExclamation mark
    GHS08,GHS07

    Signal Word

    Danger

    Hazard Statements

    H302,H360D,H362,H412

    Hazard Classifications

    Acute Tox. 4 Oral - Aquatic Chronic 3 - Lact. - Repr. 1B

    WGK

    WGK 3

    Flash Point(F)

    Not applicable

    Flash Point(C)

    Not applicable

    Certificates of Analysis (COA)

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