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BP1081

Cetirizine impurity standard

British Pharmacopoeia (BP) Reference Standard

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Synonym(s):
Cetirizine dihydrochloride, [2-[4-[(4-Chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]acetic acid dihydrochloride
Empirical Formula (Hill Notation):
C21H25ClN2O3 · 2HCl
CAS Number:
83881-52-1
Molecular Weight:
461.81
MDL number:
MFCD00941428
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

cetirizine

form

solid

shelf life

limited shelf life, expiry date on the label

manufacturer/tradename

BP

application(s)

pharmaceutical
pharmaceutical small molecule

format

mixture

storage temp.

2-8°C

SMILES string

OC(COCCN1CCN(C(C2=CC=C(Cl)C=C2)C3=CC=CC=C3)CC1)=O.[H]Cl.[H]Cl

InChI

1S/C21H25ClN2O3.2ClH/c22-19-8-6-18(7-9-19)21(17-4-2-1-3-5-17)24-12-10-23(11-13-24)14-15-27-16-20(25)26;;/h1-9,21H,10-16H2,(H,25,26);2*1H

InChI key

PGLIUCLTXOYQMV-UHFFFAOYSA-N

Gene Information

human ... HRH1(3269)

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Cetirizine impurity standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:
  • Cetirizine Capsules
  • Cetirizine Oral Solution
  • Cetirizine Tablets

    • Biochem/physiol Actions

    Cetirizine hydrochloride is an orally active and selective H1-receptor antagonist. Antihistaminic; Piperazines. Non-sedating type histamine H1-receptor antagonist; major metabolite of hydroxyzine. Pharmacological activity resides primarily in the (R)-isomer.

    Packaging

    Unit quantity: 50 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

    Other Notes

    Sales restrictions may apply.

    related product

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    Description
    Pricing

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    Cetirizine dihydrochloride, European Pharmacopoeia (EP) Reference Standard

    C0980651

    Cetirizine impurity A, European Pharmacopoeia (EP) Reference Standard

    Y0001197

    Cetirizine for peak identification, European Pharmacopoeia (EP) Reference Standard

    1102929

    Cetirizine dihydrochloride, United States Pharmacopeia (USP) Reference Standard

    1102930

    Cetirizine Related Compound A, United States Pharmacopeia (USP) Reference Standard

    PHR1656

    Cetirizine Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material

    1112467

    4-Chlorobenzophenone, United States Pharmacopeia (USP) Reference Standard

    1102952

    Cetirizine Related Compound C, United States Pharmacopeia (USP) Reference Standard

    1102941

    Cetirizine Related Compound B, United States Pharmacopeia (USP) Reference Standard

    PHR1710

    Cetirizine hydrochloride Related Compound A, Pharmaceutical Secondary Standard; Certified Reference Material

    1102963

    Cetirizine Related Compound G, United States Pharmacopeia (USP) Reference Standard

    BP837

    Cetirizine hydrochloride, British Pharmacopoeia (BP) Reference Standard

    BP441

    1,4-Bis(4-chlorobenzhydryl)piperazine, British Pharmacopoeia (BP) Reference Standard

    PHR2620

    4-Chlorobenzophenone, Pharmaceutical Secondary Standard; Certified Reference Material

    PHR2852

    Cetirizine Related Compound G, certified reference material, pharmaceutical secondary standard

    PHR3195

    Levocetirizine Dihydrochloride, pharmaceutical secondary standard, certified reference material

    Pictograms

    Exclamation mark
    GHS07

    Signal Word

    Warning

    Hazard Statements

    H302

    Hazard Classifications

    Acute Tox. 4 Oral

    WGK

    WGK 3

    Flash Point(F)

    Not applicable

    Flash Point(C)

    Not applicable

    Certificates of Analysis (COA)

    Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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