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Merck
CN

822855

TSKgel® SuperSW mAb HTP (4 µm) HPLC Column

L x I.D. 15 cm × 4.6 mm, diol phase

Synonym(s):

TSKgel® Size Exclusion (SW-Type) HPLC Column

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About This Item

UNSPSC Code:
41115711
NACRES:
NB.21

Key Documents

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Product Name

TSKgel® SuperSW mAb HTP HPLC Column, phase diol, L × I.D. 15 cm × 4.6 mm, 4 μm particle size

material

stainless steel

agency

suitable for USP L20
suitable for USP L59

product line

TSKgel®

manufacturer/tradename

Tosoh SuperSW mAb HTP, 22855

parameter

≤0.5 M salt concentration
0-100% aqueous soluble organic solvents
0.5 mL/min flow rate
10-30 °C temperature
80 bar max. pressure

technique(s)

HPLC: suitable

L × I.D.

15 cm × 4.6 mm

matrix

silica particle platform

matrix active group

diol phase

particle size

4 μm

pore size

250 Å pore size

operating pH

2.5-7.5

separation technique

size exclusion (SEC)

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General description

The TSKgel SuperSW and UltraSW mAb columns consist of three specialized columns designed for the separation and analysis of monoclonal antibodies (mAb). While mAbs can be analyzed using many different modes of HPLC, size exclusion is best for aggregation, dimer, and fragmentation, making it the best method for heterogeneity studies.TSKgel SuperSW mAb HTP columns provide high throughput analysis of mAb monomer and dimer and is UHPLC compatible. These short, narrow bore (15 cm x 4.6 mm ID) silica-based stainless steel columns offer reduced lot-to-lot variation, long column life, reduction of unspecified adsorption, and superior recovery of aggregates. The TSKgel SW mAb HTP columns utilize a unique pore-controlled technology, which produces a shallow calibration curve in the molecular weight region of a typical monoclonal antibody.

Other Notes

Discover LiChropur reagents ideal for HPLC or LC-MS analysis

Physical form

Shipped in 0.05% NaN3 and 0.1 M Na2SO4 in 0.1 M phosphate buffer, pH 6.7.

Legal Information

TSKgel is a registered trademark of Tosoh Corporation

Regulatory Information

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Articles

Columns and Analytical Standards for Protein SEC

Size-exclusion chromatography (SEC) columns and ready-to-use standards facilitate method development and increase robustness of protein SEC methods.

蛋白质SEC的色谱柱和分析标准品

体积排阻色谱（SEC）色谱柱和现成的标准品有助于方法开发，并提高蛋白质SEC方法的耐用性。

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