821946
TOYOPEARL GigaCap® CM-650M Bulk Media
phase carboxylmethyl, bottle of 100 mL, 75 μm particle size
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UNSPSC Code:
41115700
product line
TOYOPEARL®
form
slurry
feature
counter ion Na+
packaging
bottle of 100 mL
manufacturer/tradename
Tosoh 21946
parameter
3 bar max. pressure
technique(s)
LPLC: suitable
matrix
hydroxylated methacrylic polymer
matrix active group
carboxylmethyl phase
particle size
75 μm
operating pH
3-13
capacity
>110 g/L adsorption capacity (human IgG)
separation technique
cation exchange
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General description
Toyopearl GigaCap CM-650 resin is a high capacity cation exchange resin* optimized specifically for high throughput purification of IgG. Toyopearl HW-65 resin is the polymeric base bead, which is chemically modified to provide a high level of cationic binding sites for IgG. It exhibits typical dynamic binding capacities in the vicinity of 100 mg/mL for IgG. This new polymer product is stable at high linear velocities, has good pressure flow characteristics and will withstand back pressures up to 3 bar. The new higher capacity and back pressure stability of Toyopearl GigaCap CM-650 resin creates opportunities for increased throughput in downstream cation exchange purification steps.
Toyopearl GigaCap CM-650 resin has a different selectivity than Toyopearl GigaCap S-650 resin. With its unusually high capacity for a weak cationic exchange resin this selectivity may be exploited for either mAb or traditional protein purifications. Toyopearl GigaCap CM-650 resin also has excellent base stability in 0.5mol/L NaOH.
*specifically designed for packed bed use
Toyopearl GigaCap CM-650 resin has a different selectivity than Toyopearl GigaCap S-650 resin. With its unusually high capacity for a weak cationic exchange resin this selectivity may be exploited for either mAb or traditional protein purifications. Toyopearl GigaCap CM-650 resin also has excellent base stability in 0.5mol/L NaOH.
*specifically designed for packed bed use
Specifications
Clean in place with 0.5 M NaOH or 0.1 M HCl.
Physical form
72% (v/v) slurry in 20% (v/v) ethanol
Shipped in 20% (v/v) ethanol.
Legal Information
Toyopearl is a registered trademark of Tosoh Corporation
Toyopearl GigaCap is a registered trademark of Tosoh Corporation
Regulatory Information
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Certificates of Analysis (COA)
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