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Key Documents

59354-U

Supelco

Discovery® C8 (5 µm) HPLC Columns

L × I.D. 25 cm × 4.6 mm, HPLC Column

Synonym(s):

C8 Reversed-Phase Chromatography Column

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50 EA
¥2,244.00

¥2,244.00


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50 EA
¥2,244.00

About This Item

UNSPSC Code:
41115700
eCl@ss:
32110501
NACRES:
SB.52

¥2,244.00


Please contact Customer Service for Availability

Product Name

Discovery® C8 HPLC Column, 5 μm particle size, L × I.D. 25 cm × 4.6 mm

material

stainless steel column

Quality Level

Agency

suitable for USP L7

product line

Discovery®

feature

endcapped

manufacturer/tradename

Discovery®

packaging

1 ea of

extent of labeling

7.5% Carbon loading

parameter

≤70 °C temp. range
400 bar pressure (5801 psi)

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NIST1549ANIST1567BNIST3251
Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

grade

certified reference material

grade

certified reference material

grade

certified reference material

grade

certified reference material

manufacturer/tradename

NIST®

manufacturer/tradename

NIST®

manufacturer/tradename

NIST®

manufacturer/tradename

NIST®

packaging

pkg of 4 cans x 85 g

packaging

pkg of 5 pouches x 10 g ea

packaging

pkg of 50 g

packaging

pkg of 5 x 1 mL

Application

Discovery® C8 HPLC column may be used in the determination of bisphenol A, genistein, bisphenol A β-D-glucuronide (BPA gluc), and genistein 4′-β-D-glucuronide (genistein gluc) in biological matrices including urine, cultures and tissues using solid-phase microextraction (SPME), followed by high-performance liquid chromatography coupled with tandem mass spectrometry (HPLC-MS/MS).[1]

Features and Benefits

  • Excellent reproducibility
  • Faster separation of strongly hydrophobic analytes than C18 columns
  • Stable, low-bleed LC-MS separations
  • Exceptional peak shapes for basic and acidic compounds
  • Compatible with low organic/highly aqueous mobile phases

Legal Information

Discovery is a registered trademark of Merck KGaA, Darmstadt, Germany

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    Measurement of bisphenol A, bisphenol A β-d-glucuronide, genistein, and genistein 4′- β-d-glucuronide via SPE and HPLC-MS/MS.
    Coughlin LJ, et al.
    Analytical and Bioanalytical Chemistry, 401, 995-1002 (2011)
    Hugo M Botelho et al.
    Scientific reports, 5, 9038-9038 (2015-03-13)
    Plasma membrane proteins are essential molecules in the cell which mediate interactions with the exterior milieu, thus representing key drug targets for present pharma. Not surprisingly, protein traffic disorders include a large range of diseases sharing the common mechanism of
    G L Bundy et al.
    The Journal of biological chemistry, 261(2), 747-751 (1986-01-15)
    The gorgonian coral Pseudoplexaura porosa contains a lipoxygenase capable of converting exogenous arachidonic acid into (8R)-8-hydroperoxy-5,9,11,14-eicosatetraenoic acid. The (8R)- (or 8-L-) configuration in this product, opposite to that observed in previously reported 8-lipoxygenase products, was determined unambiguously by comparison of
    M Q Zhang et al.
    Die Pharmazie, 46(10), 687-700 (1991-10-01)
    The rapid growth in the quinolone research changed the whole face of the previous SAR concepts. So far structural modifications at all positions of the quinolone nucleus except the 4-oxo group have successfully lead to the discovery of potent antimicrobial
    Bo-Rui Kang et al.
    Bioorganic & medicinal chemistry letters, 25(24), 5808-5812 (2015-11-08)
    2-Benzylisoquinolin-1(2H)-ones has been proposed as vasodilative agents on the basis of scaffold hopping. In the present study, a series of 2-benzylisoquinolin-1(2H)-ones were synthesized. Their vasodilative effects were evaluated by wire myograph on isolated rat mesenteric arterial ring induced contraction with

    Related Content

    Discovery C18 and C8 HPLC Columns products offered

    Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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