58348
SUPELCOSIL™ LC-18-DB (5 µm) HPLC Columns
L × I.D. 15 cm × 4.6 mm, HPLC Column
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About This Item
UNSPSC Code:
41115700
eCl@ss:
32110501
Recommended Products
Product Name
SUPELCOSIL™ LC-18-DB HPLC Column, 5 μm particle size, L × I.D. 15 cm × 4.6 mm
Agency
suitable for USP L1
Quality Level
feature
endcapped
manufacturer/tradename
SUPELCOSIL™
extent of labeling
11.0% Carbon loading
parameter
0-70 °C temperature
400 bar pressure (5801 psi)
technique(s)
HPLC: suitable
L × I.D.
15 cm × 4.6 mm
surface area
170 m2/g
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General description
SUPELCOSIL LC-DB phases are specially deactivated for basic compounds. These columns provide shorter retention, better peak shape, and higher efficiency for organic bases than can be obtained on other Type A silica reversed-phase columns.
Application
SUPELCOSIL™ LC-18-DB HPLC Column has been used for the separation of:
- Analytes of pharmaceutical relevance during their analysis using LC in conjunction with principal component analysis (PCA).
- Loratadine in human plasma during its analysis by using HPLC combined with ultraviolet (UV) detection.
Legal Information
SUPELCOSIL is a trademark of Sigma-Aldrich Co. LLC
guard cartridge
Product No.
Description
Pricing
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Determination of loratadine in human plasma by high-performance liquid chromatographic method with ultraviolet detection.
Kunicki PK.
Journal of Chromatography. B, Biomedical Sciences and Applications, 755(1-2), 331-335 (2001)
Chromatographic classification and comparison of commercially available reversed-phase liquid chromatographic columns using principal component analysis
Euerby MR and Petersson P
Journal of Chromatography A, 994(1-2), 13-36 (2003)
Jaganathan Subramani et al.
Aging, 12(19), 19809-19827 (2020-10-14)
Aging is an independent risk factor for cardiovascular diseases, such as myocardial infarction due to ischemia-reperfusion injury (I/R) of the heart. Cytosolic thioredoxin (Trx) is a multifunctional redox protein which has antioxidant and protein disulfide reducing properties. We hypothesized that
J S Patrick et al.
Analytical biochemistry, 199(1), 125-131 (1991-11-15)
A rapid, isocratic method for the determination of tryptophan in Escherichia coli fermentation broths by reversed-phase HPLC is described. Tryptophan can be measured in fermentations containing either chemically defined media or media with hydrolyzed protein supplements. The procedure was rugged
P K Kunicki
Journal of chromatography. B, Biomedical sciences and applications, 755(1-2), 331-335 (2001-06-08)
A HPLC-UV determination of loratadine in human plasma is presented. After simple liquid-liquid extraction with 2-methylbutane-hexane (2:1) and evaporation of organic phase the compounds were re-dissolved in 0.01 M HCl, evaporated again and finally separated on a Supelcosil LC-18-DB column.
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