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568523-U

Supelco

Discovery® HS C18 (5 µm) HPLC Columns

L × I.D. 25 cm × 4.6 mm, HPLC Column

Synonym(s):

Discovery RP18 HPLC Column

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About This Item

UNSPSC Code:
41115700
eCl@ss:
32110501
NACRES:
SB.52
Product 568523-U is not currently sold in your country. Contact Technical Service

Product Name

Discovery® HS C18 HPLC Column, 5 μm particle size, L × I.D. 25 cm × 4.6 mm

material

stainless steel column

Agency

suitable for USP L1

product line

Discovery®

feature

endcapped

manufacturer/tradename

Discovery®

packaging

1 ea of

extent of labeling

20% Carbon loading

parameter

≤70 °C temp. range
400 bar pressure (5801 psi)

technique(s)

HPLC: suitable
LC/MS: suitable

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Show Differences

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H6278579002E8284
(Z)-4-羟三苯氧胺 ≥98% Z isomer

H7904

(Z)-4-羟三苯氧胺

4-羟基他莫西芬 ≥70% Z isomer (remainder primarily E-isomer)

H6278

4-羟基他莫西芬

(Z)-4-羟基-三苯氧胺，大包装 A cell-permeable, active metabolite of Tamoxifen that acts as a potent inhibitor of PKC. It is more potent than the parent compound and inhibits PKC by modifying its catalytic domain.

579002

(Z)-4-羟基-三苯氧胺，大包装

(E/Z)-盐酸内多昔芬水合物 ≥98% (HPLC)

E8284

(E/Z)-盐酸内多昔芬水合物

form

powder

form

powder

form

solid

form

solid

Quality Level

300

Quality Level

300

Quality Level

200

Quality Level

100

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage condition

desiccated, protect from light

storage condition

desiccated, protect from light

storage condition

OK to freeze

storage condition

desiccated

solubility

ethanol: 20 mg/mL (with heating), methanol: 10 mg/mL

solubility

methanol: 10 mg/mL, ethanol: 20 mg/mL (with heating)

solubility

methanol: 10 mg/mL, ethanol: 20 mg/mL (heating may be required)

solubility

DMSO: >10 mg/mL

General description

Discovery® HS C18 HPLC column has been used in investigating the effect of essential oils on aromatherapy workplaces on volatile organic compounds variations and the formation of secondary air pollutants such as formaldehyde and secondary organic aerosols (SOAs).[1]

Features and Benefits

  • Stable, low bleed for LC-MS applications
  • Scalable from analytical to preparatory
  • Highly stable to ensure excellent run-to-run and lot-to-lot reproducibility
  • Higher hydrophobicity for better resolution of difficult analytes
   

Recommended products

Discover LiChropur reagents ideal for HPLC or LC-MS analysis

Legal Information

Discovery is a registered trademark of Merck KGaA, Darmstadt, Germany

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  • Specification Sheet

    • Choose from one of the most recent versions:

    Certificates of Analysis (COA)

    Lot/Batch Number
    294604-06
    294604-05
    294604-04
    294604-03
    294604-02

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    Effects of essential oils on the formation of formaldehyde and secondary organic aerosols in an aromatherapy environment.
    Huang L-H
    Building and Environment, 57, 20-125 (2012)
    Abad Khan et al.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 878(28), 2782-2788 (2010-09-11)
    A rapid, inexpensive, sensitive and specific HPLC-ECD method for the determination of lipoic acid in human plasma was developed and validated over the linearity range of 0.001-10μg/ml using naproxen sodium as an internal standard (IS). Extraction of lipoic acid and
    Fazli Khuda et al.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 944, 114-122 (2013-12-10)
    A simple, specific, precise and rapid RP-HPLC-UV method was developed for simultaneous determination of lumefantrine and its metabolite desbutyl lumefantrine in human plasma. Experimental parameters were optimized and the method was validated according to standard guidelines. The method showed adequate
    Lucie Zelena et al.
    Journal of pharmaceutical and biomedical analysis, 137, 70-77 (2017-01-17)
    Efavirenz is an antiretroviral drug used in the treatment of HIV-positive patients. A simple, fast and sensitive high-performance liquid chromatography (HPLC) method was developed in order to determine efavirenz in three types of samples provided from pharmacokinetic studies. The analysis
    Steinar Uran et al.
    Journal of pharmaceutical and biomedical analysis, 44(4), 947-954 (2007-05-08)
    Injection of hyperpolarized (13)C-labelled pyruvate ((13)C pyruvate) is under evaluation as an agent for medical metabolic imaging by measuring formation of (13)C lactate using magnetic resonance spectroscopy of the (13)C nuclei. A quantitative method for analysis of these (13)C-labelled substances
    View All Related Papers

    Articles

    Ephedrine/Pseudoephedrine Determination

    Discovery® C18 column aids in HPLC method development for quantifying ephedrine and pseudoephedrine in traditional Chinese medicine.

    Determination of Chlorogenic acid and Baicalin in Compounded Lonucerae Japonicae Flos using a Discovery® HS C18 Column

    Extraction and analyses of chlorogenic acid and baicalin active ingredients in traditional Chinese medicine (TCM) according to Chinese pharmacopeia monograph by HPLC with Discovery® C18 column to check: chromatographic data, linearity, specificity and repeatability, LOQ and LOD

    Determination of Baicalin, Chlorogenic acid and Forsythin

    Analyze Shuanghuang Lian oral liquid using Discovery® HS C18 HPLC column per Chinese Pharmacopeia 2020. Quantify baicalin, chlorogenic acid, and forsythin with high accuracy.

    Determination of Geniposide Forsythin in XiaoerChiqiaoQingre

    Analyze Xiaoer Chiqiao Qingre granules for geniposide and forsythin using Discovery® HS C18 column and Supelclean™ LC-Alumina-N SPE.

    Related Content

    HPLC Discovery HS C18

    HPLC DiscoveryBIO HS C18 products. Available in 3µm, 5µm and 10µm particle sizes.

    Chromatograms

    application for HPLCapplication for HPLCapplication for HPLCapplication for HPLC

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