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About This Item
NACRES:
NB.21
UNSPSC Code:
41115712
material
polypropylene tube
composition
bed weight, 100 mg
packaging
pk of 50
technique(s)
solid phase extraction (SPE): suitable
volume
3 mL
matrix active group
amino phase, carbon phase
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General description
The SupelMIP SPE line consist s of highly cross-linked polymers that are engineered to extract a single analyte of interest or a class of structurally related analytes with an extremely high degree of selectivity. This is possible because selectivity is introduced during MIP synthesis in which a template molecule, designed to mimic the analyte, guides the formation of specific cavities or imprints that are sterically and chemically complementary to the analyte(s) of interest.
By careful design of the imprinting site, either by molecular modeling, experimental design, or screening methods, the binding cavities can be engineered to offer multiple interaction points with the analyte(s) of interest. This leads to a stronger interaction between the solid-phase and the analyte(s). As a consequence, harsher wash conditions can be tolerated during SPE methodology resulting in cleaner extracts. Because extraction selectivity is significantly improved, lower background is observed allowing analysts to achieve lower limits of detection.
Visit www.sigma-aldrich.com/supelmip to learn more.
By careful design of the imprinting site, either by molecular modeling, experimental design, or screening methods, the binding cavities can be engineered to offer multiple interaction points with the analyte(s) of interest. This leads to a stronger interaction between the solid-phase and the analyte(s). As a consequence, harsher wash conditions can be tolerated during SPE methodology resulting in cleaner extracts. Because extraction selectivity is significantly improved, lower background is observed allowing analysts to achieve lower limits of detection.
Visit www.sigma-aldrich.com/supelmip to learn more.
Application
Developed for the class-selective extraction of Bisphenol A (BPA) from broth or milk-based matrices.
Features and Benefits
- Highly selective SPE for trace analysis in complex matrices
- Achieve lower detection limits
- Significant time and cost savings
- Improved MS-compatibility
Legal Information
SupelMIP is a registered trademark of Sigma-Aldrich Co. LLC
Regulatory Information
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Related Content
SupelMIP SPE is based on molecularly imprinted polymer (MIP) technology. Each SupelMIP phase offers tailor-made selectivity for the extraction of trace analytes in complex matrixes.
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
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