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50659-U

BIOshell^™ A160 Peptide PCS-C18, 2.7 µm HPLC Column

Name: BIOshell<SUP>™</SUP> A160 Peptide PCS-C18, 2.7 µm HPLC Column
Brand: SUPELCO

column L × I.D. 150 mm × 2.1 mm, pk of 1 ea

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About This Item

NACRES:

SB.52

UNSPSC Code:

41115709

Matrix active group:

C18 bonding phase, dimethyloctadecylsilane and positively charged ligand

Matrix:

superficially porous particle particle platform (Fused-Core^®)

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Properties

CofA

current certificate can be downloaded

Quality Level

100

packaging

pk of 1 ea

extent of labeling

5.1% Carbon loading

parameter

600 bar max. pressure (8700 psi)

maximum temperature

60 °C (pH2/60; pH7/40)

column L × I.D.

150 mm × 2.1 mm

surface area

75 m²/g

matrix

superficially porous particle particle platform (Fused-Core^®)

matrix active group

C18 bonding phase, dimethyloctadecylsilane and positively charged ligand

operating pH range

2-7

Description

General description

BIOshell^™ A160 Peptide PCS-C18 columns are specifically engineered to provide efficient separation of peptides as well as small proteins. These columns contain advanced Fused-Core® particles with pores strategically sized to 160 Å to enable optimized peptide diffusion. This attribute makes these columns an excellent choice for peptide mapping. The unique PCS-C18 chemistry enables exceptional peak shape and enhanced loading capacity of basic peptides as compared to traditional C18 chemistries. In addition, the PCS-C18 facilitates the use of mobile phases with lower concentrations of mobile phase modifiers without any compromise to column performance. This column also provides orthogonal selectivity to ES-C18, ES-CN (cyano), and phenyl-hexyl chemistries.

Analysis Note

Target analytes include peptides, proteins (< 25 kDa MW), tryptic digests, and post-translationally modified (PTM) peptides and polypeptides.

Legal Information

BIOshell is a trademark of Sigma-Aldrich Co. LLC

Fused-Core is a registered trademark of Advanced Materials Technology, Inc.

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Articles

Quantification of Liraglutide GLP-1 Analogue

Accurate LC-MS-based analysis of GLP-1 agonist drug liraglutide in human plasma samples using BIOshell™ A160 Peptide PCS-C18 column.

Analysis of Compounded Semaglutide Impurities on C18 Column

LC-MS-based analysis of GLP-1 agonist drug semaglutide for detection of a key N-terminal impurity using BIOshell™ A160 Peptide PCS-C18 column.

Analysis of Liraglutide on BIOshell PCS-C18 Column

LC-MS/MS analysis of GLP-1 agonist drug liraglutide for identification of N-terminal cyclization impurity using BIOshell™ A160 Peptide PCS-C18 column.

Global Trade Item Number

SKU	GTIN
50659-U	04065270862136