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Merck
CN

40060

N-Nitrosodiphenylamine solution

certified reference material, 5000 μg/mL in methanol

Synonym(s):

N-Nitroso-N-phenylaniline, Diphenylnitrosamine, Diphenylnitrosoamine

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About This Item

CAS Number:
MDL number:
UNSPSC Code:
41116105
EC Number:
200-659-6
NACRES:
NA.24
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SMILES string

N(N=O)(c2ccccc2)c1ccccc1

InChI key

UBUCNCOMADRQHX-UHFFFAOYSA-N

InChI

1S/C12H10N2O/c15-13-14(11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1-10H

grade

certified reference material, TraceCERT®

agency

EPA 625,8270,Mar ′90, Dec ′90, Aug ′91 Statement of Work, EPA OLM04 (Statement of Work)

product line

TraceCERT®

CofA

current certificate can be downloaded

feature

standard type calibration

packaging

ampule of 1 mL

concentration

5000 μg/mL in methanol

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

environmental

format

single component solution

storage temp.

2-8°C

Quality Level

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Legal Information

TraceCERT is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 3 - Flam. Liq. 2 - Skin Sens. 1 - STOT SE 1

target_organs

Eyes,Central nervous system

Storage Class

3 - Flammable liquids

wgk

WGK 2

flash_point_f

49.5 °F

flash_point_c

9.7 °C

Regulatory Information

危险化学品
This item has

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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J W Dallinga et al.
European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP), 10(3), 265-268 (2001-07-04)
The thermal energy analyser (TEA) is considered to be the gold standard for the determination of nitrosamines. However, since many laboratories cannot justify the use of such a very specific detection system, alternative detection methods are useful. While standard gas
[N-nitrosamines in the air of an enterprise producing rubber footwear and rubber technology articles].
L G Solenova et al.
Gigiena truda i professional'nye zabolevaniia, (6)(6), 23-25 (1990-01-01)
Wenjun Zhou et al.
Journal of environmental sciences (China), 24(7), 1217-1224 (2012-01-01)
Disinfection by-products (DBPs) in drinking water have caused worldwide concern due to their potential carcinogenic effects. The formation of phenazine from diphenylamine (DPhA) chloramination was studied and its cytotoxicities for two human cancer cells were also investigated. Phenazine was detected
K E Appel et al.
Journal of cancer research and clinical oncology, 113(2), 131-136 (1987-01-01)
Nitrosodiphenylamine was tested for induction of DNA single strand breaks in rat hepatocytes and Chinese hamster V 79 cells with the alkaline filter elution assay. While in rat hepatocytes DNA damage was observed, negative results were obtained in V 79
K E Appel et al.
IARC scientific publications, (84)(84), 117-123 (1987-01-01)
The present paper deals with three aspects of cytochrome P450-dependent denitrosation of N-nitrosamines. (1) Nitrate was found in addition to nitrite as a metabolic product of the denitrosation reaction when N-nitrosamines were incubated with a microsomal system. This could also

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