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Synonym(s):
Chlorotrimethylsilane, N,O-Bis(trimethylsilyl)trifluoroacetamide, Trimethylchlorosilane, Trimethylsilyl chloride
UNSPSC Code:
12000000
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grade
for derivatization (GC/GC-MS)
Quality Level
description
(SYLON BFT)
reaction suitability
reagent type: derivatization reagent
reaction type: Silylations
packaging
pkg of 1 × 25 mL
concentration
(BSTFA+TMCS, 99:1)
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General description
BSTFA is a stronger silylating reagent compared to BSA. In most cases, BSTFA is used in place of BSA as the reaction products are more volatile avoiding interference with early peaks in a chromatogram. BSTFA along with TMCS is considered suitable reagent for quantitative reactions.
Application
It was used in the derivatization of water during determination of trace levels of bisphenol A from plastic water containers using solid-phase microextraction (SPME) coupled with GC-MS.
Other Notes
Reagent for isothiocyanate (amino compounds), oxime, trimethylsilyl (TMS), trimethylsilyl deacylated polyphosphoinositides and trimethylsilyl glycerophosphate esters.
related product
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2
WGK
WGK 3
Flash Point(F)
closed cup
Flash Point(C)
closed cup
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
危险化学品
Certificates of Analysis (COA)
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Ryan R Lappe et al.
Proceedings of the National Academy of Sciences of the United States of America, 115(1), E24-E33 (2017-12-20)
Maize
Combined gas chromatography-mass spectrometry of brain polyphosphoinositides.
T J Cicero et al.
Biochemical and biophysical research communications, 42(3), 428-433 (1971-02-05)
N.Narasimhachari et al.
Journal of Chromatographic Science, 9, 502-502 (1971)
Mass spectra of prostaglandins. IV. Trimethylsilyl derivatives of prostaglandins of the F series.
B S Middleditch et al.
Analytical biochemistry, 55(2), 509-520 (1973-10-01)
D.R. Knapp
Handbook of Analytical Derivatization Reactions, 214-214 (1979)
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