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33154-U

Supelco

BSTFA + TMCS, 99:1

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Synonym(s):
Chlorotrimethylsilane, N,O-Bis(trimethylsilyl)trifluoroacetamide, Trimethylchlorosilane, Trimethylsilyl chloride
UNSPSC Code:
12000000

grade

for derivatization (GC/GC-MS)

description

(SYLON BFT)

reaction suitability

reagent type: derivatization reagent
reaction type: Silylations

packaging

pkg of 144 × 0.1 mL

concentration

(BSTFA + TMCS, 99:1)

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General description

BSTFA is a stronger silylating reagent compared to BSA. In most cases, BSTFA is used in place of BSA as the reaction products are more volatile avoiding interference with early peaks in a chromatogram. BSTFA along with TMCS is considered suitable reagent for quantitative reactions.

Application

It was used in the derivatization of water during determination of trace levels of bisphenol A from plastic water containers, using solid-phase microextraction (SPME) coupled with GC-MS.

Other Notes

Reagent for trimethylsilyl (TMS).

Pictograms

FlameExclamation mark
GHS02,GHS07

Signal Word

Warning

Hazard Statements

H226,H315,H319

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2

WGK

WGK 3

Flash Point(F)

closed cup

Flash Point(C)

closed cup

Regulatory Information

危险化学品

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. What is the role of TMCS in product number 33154-U, BSTFA & TMCS, 99:1, Sylon BFT?

    TMCS acts as a catalyst for the BSTFA to react with the protic sites of the compound of interest.

  4. What is the shelf life of product number 33154-U, BSTFA & TMCS, 99:1, Sylon BFT?

    Properly stored, this reagent is stable indefinitely.  However, once opened, the presence of moisture can degrade the reactivity of this reagent.

  5. How do I know when the reaction is complete when using product number 33154-U, BSTFA & TMCS, 99:1, Sylon BFT?

    It is recommended that you sample the reaction at various time intervals for analysis.  Once you see that the response of the analyte of interest levels off, the reaction should be complete.

  6. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  7. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

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    Ask a Scientist here.

D.R. Knapp
Handbook of Analytical Derivatization Reactions, 214-214 (1979)
N.Narasimhachari et al.
Journal of Chromatographic Science, 9, 502-502 (1971)
Mass spectra of prostaglandins. IV. Trimethylsilyl derivatives of prostaglandins of the F series.
B S Middleditch et al.
Analytical biochemistry, 55(2), 509-520 (1973-10-01)
A J Poole et al.
Clinica chimica acta; international journal of clinical chemistry, 73(3), 527-535 (1976-12-01)
Evidence is presented to confirm that N,O-bis(trimethylsilyl)acetamide does not form trimethylsilyl derivatives of sodium salts of many organic acids. Further evidence suggests that such derivatives are formed when either hydroxylamine hydrochloride or trimethylchlorosilane are also present. This presents a useful
Determining leaching of bisphenol A from plastic containers by solid-phase microextraction and gas chromatography-mass spectrometry.
Chang, Chia-Min, Chi-Chi Chou, and Maw-Rong Lee.
Analytica Chimica Acta, 539, 41-47 (2005)
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