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33051

Supelco

Methanolic HCl

3 M HCl in methanol (3N), for GC derivatization, ampule of 10 × 3 mL

Synonym(s):

Hydrogen chloride, Hydrochloric acid solution

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About This Item

Empirical Formula (Hill Notation):
HCl
CAS Number:
7647-01-0
Molecular Weight:
36.46
UNSPSC Code:
41116105
PubChem Substance ID:
24859867

grade

for GC derivatization

reaction suitability

reagent type: derivatization reagent
reaction type: Esterifications

packaging

ampule of 10 × 3 mL

concentration

3 M HCl in methanol (3N)

storage temp.

2-8°C

InChI

1S/ClH/h1H

InChI key

VEXZGXHMUGYJMC-UHFFFAOYSA-N

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General description

Methanolic HCl (hydrochloric acid in methanol) is particularly useful for preparing methyl esters of volatile (short chain) fatty acids. Fatty acids are esterified by heating them with an anhydrous alcohol (e.g., methanol) in the presence of an acidic catalyst (e.g., HCl) in a sealed vessel at a high temperature for a short time. In the reaction, a fatty acid molecule and an alcohol molecule are joined, with the release of a water molecule. The derivatives can be quickly and easily recovered, quantitatively, from the reaction medium.

Features and Benefits

  • Derivatization of fatty acids, particularly volatile (short chain) fatty acids.

  • Clean reaction (no side reaction) with volatile by-products.

  • Provides clean, fast, quantitative derivatization.

related product

Product No.
Description
Pricing

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - Met. Corr. 1 - STOT SE 1

Target Organs

Eyes,Central nervous system

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

51.8 °F - closed cup

Flash Point(C)

11 °C - closed cup

Regulatory Information

新产品

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
LC26492V
LC24878V
LC23598V
LC22017V
LC21651V

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  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. When using 3N Methanolic HCl, Product 33051, how long should I let the reaction go?

    The typical procedure for forming methyl esters will have the mixture heated at 50°C for 5-10 minutes.  However, we recommend that you sample at other time intervals to ensure that your reaction has gone to completion.

  4. With which compounds should I use the Methanolic HCl, Product 33051?

    The  3N Methanolic HCl reagent works best for derivatizing short chain fatty acids (C4-C8).  However, it can be used for C9 and longer, but you may see a decrease in recoveries for some of the longer chains.

  5. Is Product 33051, Methanolic HCl, only used to make derivatives for GC analysis?

    The methyl esters formed by use of this reagent can be used for both TLC and HPLC applications.

  6. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  7. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  8. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

Mitochondrial Function, Part B: Mitochondrial Protein Kinases, Protein Phosphatases and Mitochondrial Diseases.
William SA and Murphy AN.
Science, 88-89 (2009)
Practical Gas Chromatography: A Comprehensive Reference.
Wilder KD and Engewald W.
Science, 613-614 (2014)
Enamel color modifications by controlled hydrochloric acid pumice abrasion: a review with case summaries.
T C Adams
Journal (Indiana Dental Association), 66(5), 23-26 (1987-09-01)
Enamel color modifications by controlled hydrochloric acid pumice abrasion: a review with case summaries.
T C Adams
Journal of the Massachusetts Dental Society, 39(4), 181-183 (1990-01-01)
[Fluid and electrolyte movements through the gastrointestinal membranes: hydrochloric acid formation and intestinal water transport].
D P Mertz
Klinische Wochenschrift, 45(2), 57-68 (1967-01-15)
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