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Merck
CN

33035-U

BSA Derivatization Grade

derivatization grade, Silylation reagent

Synonym(s):

N,O-Bis(trimethylsilyl)acetamide

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About This Item

EC Number:
233-892-7
UNSPSC Code:
23151816
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grade

derivatization grade ((GC derivatization)), derivatization grade

reaction suitability

reagent type: derivatization reagent
reaction type: Silylations

packaging

pkg of 144 × 0.1 mL (33035-U)

General description

BSA (N,O-Bis(trimethylsilyl)acetamide) is a powerful reagent for silyation of alkyl hydroperoxides. It reacts quantitatively under mild conditions with alcohols, amines, phenols and carboxylic acids which gives trimethylsilyl ethers and esters.

Application

BSA was used in silyation procedure of amino acid phenylthiohydantoin standards during GC analysis.

Other Notes

Reagent for 1,3-dipheylimidazolidine-2-carboxylic acid, o-ethyloxime, quinoxalone, trimethylsilyl and trimethylsilyl oximes.

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Danger

Hazard Classifications

Acute Tox. 4 Oral - Flam. Liq. 3 - Skin Corr. 1B

supp_hazards

Storage Class

3 - Flammable liquids

wgk

WGK 3

flash_point_f

111.2 °F - closed cup

flash_point_c

44 °C - closed cup

Regulatory Information

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D.R. Knapp
Handbook of Analytical Derivatization Reactions, 202-214 (1979)
Quantitative analysis of branched-chain alpha-keto acids as their trimethylsilylated oximes.
G Lancaster et al.
Clinica chimica acta; international journal of clinical chemistry, 48(3), 279-285 (1973-10-30)
J.L. Cashaw et al.
Journal of Chromatographic Science, 9, 98-98 (1971)
Gas chromatography of some urinary acid metabolites related to phenylketonuria.
N E Hoffman et al.
Analytical biochemistry, 31(1), 471-479 (1969-10-01)
Richard F. Venn
Principles and Practice of Bioanalysis, 147-147 (2000)

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