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20324AST

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Astec® CYCLOBOND I 2000 RSP Chiral (5 μm) HPLC Columns

L × I.D. 25 cm × 4.6 mm, HPLC Column

Synonym(s):

Chiral HPLC column 2000 RSP

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About This Item

UNSPSC Code:
41115700
eCl@ss:
32110501
NACRES:
SB.52

Pricing and availability is not currently available.

Product Name

Astec® CYCLOBOND I 2000 RSP Chiral HPLC Column, 5 μm particle size, L × I.D. 25 cm × 4.6 mm

material

stainless steel column

Quality Level

Agency

suitable for USP L45

product line

Astec®

packaging

pkg of 1 ea

manufacturer/tradename

Astec®

parameter

0-50 °C temperature
172 bar pressure (2500 psi)

technique(s)

HPLC: suitable
LC/MS: suitable

L × I.D.

25 cm × 4.6 mm

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1 of 4

This Item
466190T119945979
assay

≥99.5% (GC)

assay

98%

assay

-

assay

-

solubility

H2O: slightly soluble

solubility

H2O: slightly soluble

solubility

-

solubility

H2O: slightly soluble

Quality Level

100

Quality Level

200

Quality Level

200

Quality Level

100

form

liquid

form

liquid

form

-

form

-

mp

−28 °C (lit.)

mp

−28 °C (lit.)

mp

-

mp

−28 °C (lit.)

density

1.008 g/mL at 25 °C (lit.)

density

1.008 g/mL at 25 °C (lit.)

density

-

density

1.008 g/mL at 25 °C (lit.)

General description

The hydroxyl groups on the surface of the β-cyclodextrin are reacted with (R,S)-propylene oxide to yield a general purpose chiral stationary phase. It has the added property of separating non-aromatic structures such as t-boc amino acids, for which it is a standard methodology.

  • Bonded phase: (R,S)-Hydroxypropyl modified β-cyclodextrin

Application

Astec® CYCLOBOND I 2000 RSP chiral HPLC column is basically comprised of native and derivatized β and γ cyclodextrins.[1] It has been used for numerous chiral separations via selectively trapping the organic molecules in the cyclodextrin cavity.[1]

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Legal Information

Astec is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Rare case of rhabdomyolysis with therapeutic doses of phendimetrazine tartrate.
DK, et al.
American Journal of Therapeutics, 13(2), 175-176 (2006)
Liquid chromatographic separation of zalcitabine and its stereoisomers
Scypinski, Stephen; Ross, Arthur J.
Journal of Chromatography. B, Biomedical Sciences and Applications, 12 (10), 1271-1276 (1994)
C Pham-Huy et al.
Journal of chromatography. B, Biomedical sciences and applications, 700(1-2), 155-163 (1997-12-09)
The simultaneous determination of methadone (Mtd) enantiomers and its major metabolite, 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine (EDDP), in human urine and serum by enantioselective HPLC using a new Cyclobond 1-2000 RSP column is described. After alkaline extraction from urine or serum with estazolam as
Solid-phase extraction of methadone enantiomers and benzodiazepines in biological fluids by two polymeric cartridges for liquid chromatographic analysis
He, Hua, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 814 (2), 385-391 (2005)
High-performance liquid chromatographic determination of the isomeric purity of a series of dioxolane nucleoside analogues
Di Marco, M.P., et al.
Journal of Chromatography A, 645 (1), 107-114 (1993)

Related Content

CYCLOBOND is the name given to Astec technology for bonding cyclodextrins to a high purity silica gel through a stable ether linkage.

Chromatograms

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