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11022AST

Supelco

Astec® CHIROBIOTIC® V Chiral (5 μm) HPLC Columns

L × I.D. 10 cm × 4.6 mm, HPLC Column

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CN¥8,017.76

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About This Item

UNSPSC Code:
41115700
eCl@ss:
32110501
NACRES:
SB.52

CN¥8,017.76

Please contact Customer Service for Availability

Product Name

Astec® CHIROBIOTIC® V Chiral HPLC Column, 5 μm particle size, L × I.D. 10 cm × 4.6 mm

material

stainless steel column

Agency

suitable for USP L88

description

HPLC Column

product line

Astec®

packaging

pkg of 1 ea

manufacturer/tradename

Astec®

parameter

0-45 °C temperature
241 bar pressure (3500 psi)

technique(s)

HPLC: suitable
LC/MS: suitable

L × I.D.

10 cm × 4.6 mm

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Headspace vial, screw top, rounded bottom (vial only) volume 20 mL, amber glass vial, thread for 18, O.D. × H 22.5 mm × 75.5 mm, pkg of 100 ea

SU860098

Headspace vial, screw top, rounded bottom (vial only)

Headspace vial, screw top, rounded bottom (vial only) volume 10 mL, clear glass vial, thread for 18, O.D. × H 22.5 mm × 46 mm, pkg of 100 ea

SU860099

Headspace vial, screw top, rounded bottom (vial only)

Headspace vial, beveled top, rounded bottom volume 20 mL, clear glass vial, O.D. × H × I.D. 23 mm × 75.5 mm × 12.5 mm, for use with PerkinElmer, pkg of 100 ea

SU860049

Headspace vial, beveled top, rounded bottom

material

clear glass vial, round bottom

material

amber glass vial, round bottom

material

clear glass vial, round bottom

material

clear glass vial, round bottom

fitting

thread for 18

fitting

thread for 18

fitting

thread for 18

fitting

thread for 20 mm

volume

20 mL

volume

20 mL

volume

10 mL

volume

20 mL

compatibility

for use with CTC PAL (Varian, Gerstel, Atas, Shimadzu)

compatibility

for use with CTC PAL (Varian, Gerstel, Atas, Shimadzu)

compatibility

for use with CTC HTC PAL, for use with CTC PAL (Varian, Gerstel, Atas, Shimadzu)

compatibility

for use with PerkinElmer

packaging

pkg of 100 ea

packaging

pkg of 100 ea

packaging

pkg of 100 ea

packaging

pkg of 100 ea

General description

Neutral molecules, amides, acids, esters and amines show considerable enantioselectivity on these vancomycin-based CSPs. A wide variety of secondary and tertiary amines have been separated on the CHIROBIOTIC® V in the polar ionic mode. The CHIROBIOTIC® V has demonstrated many of the separation characteristics of protein-based stationary phases, but with exceptional stability and much higher sample capacity. Some chiral analytes have been resolved that have not been reported separated on any other chiral stationary phase. CHIROBIOTIC® V and V2 differ in their bonding chemistry the pore size of the support particle, giving them different selectivity and preparative capacity.

  • Bonded phase: Vancomycin
  • Operating pH range: 3.5 - 7.0
  • Particle diameter: 5, 10 or 16 μm
  • Pore size: 100 Å (CHIROBIOTIC® V) or 200 Å (CHIROBIOTIC® V2)

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Legal Information

Astec is a registered trademark of Merck KGaA, Darmstadt, Germany
CHIROBIOTIC is a registered trademark of Sigma-Aldrich Co. LLC

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    Certificates of Analysis (COA)

    Lot/Batch Number
    289389-06
    289389-05
    289389-04
    289389-03
    289389-02

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    Enantiomeric separation of mirtazapine and its metabolite in rat plasma by reverse polar ionic liquid chromatography using fluorescence and polarimetric detectors connected in series
    Rao, R. Nageswara, et al.
    Journal of Chromatography. B, Biomedical Sciences and Applications, 879 (21), 1911-1916 (2011)
    Chiral stability-indicating HPLC method for analysis of arotinolol in pharmaceutical formulation and human plasma
    Sultan, Maha A., et al.
    Arabian Journal of Chemistry, 3 (3), 147-153 (2010)
    Ana R Ribeiro et al.
    Chemosphere, 95, 589-596 (2013-11-05)
    Microbial degradation is the most important process to remove organic pollutants in Waste Water Treatment Plants. Regarding chiral compounds this process is normally enantioselective and needs the suitable analytical methodology to follow the removal of both enantiomers in an accurate
    Hisham Hashem et al.
    Journal of chromatography. A, 1218(38), 6727-6731 (2011-08-23)
    In this study, a method for enantioseparation of terbutaline and salbutamol was established using Chirobiotic V column as a stationary phase. Polar ionic mode applying mobile phase containing ammonium nitrate in 100% ethanol, pH 5.1 was found to give the
    HPLC separation technique for analysis of bufuralol enantiomers in plasma and pharmaceutical formulations using a vancomycin chiral stationary phase and UV detection
    Hefnawy, Mohamed M., et al.
    Journal of Chromatography. B, Biomedical Sciences and Applications, 856 (1-2), 328-336 (2007)
    View All Related Papers

    Protocols

    Chiral and Achiral LC-MS Analysis of Warfarin™ in Plasma Samples

    This study demonstrates the analysis of Warfarin in plasma samples utilizing chiral and achiral (reversed-phase) LC-MS and effective sample prep to remove endogenous phospholipids

    Chromatograms

    suitable for GCapplication for HPLC

    Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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