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10264

Supelco

Carboxen® Adsorbent

matrix Carboxen® 564, 20-45 mesh, bottle of 10 g

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EC Number:
UNSPSC Code:
23201100

product line

Carboxen®

Quality Level

form

powder

packaging

bottle of 10 g

technique(s)

LPLC: suitable

surface area

~400 m2/g

matrix

Carboxen® 564

matrix active group

carbon

particle size

20-45 mesh

pore size

~0.13 cm3/g mesoporosity
~0.14 cm3/g macroporosity
~0.24 cm3/g microporosity
~6-9 Å pore diameter

density

~0.61 g/mL (free fall density)

separation technique

reversed phase

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General description

Carboxens are a highly engineered synthetic carbon adsorbent engineered from polymeric precursors. These particles will not plastically deform like resins or generate fines like activated carbon. These materials are shipped and stored dried. These derivatized resins bring value to a wide range of purification applications for removing both small and large molecule impurities. They find use in both gas and liquid phase purifications. Some examples include removal of homogenous catalysts from active pharmaceutical ingredients (API)s, high-risk impurities in biochemical purifications such as host cell proteins from mAbs, removal of toxic heavy metals, purification of chlorinated molecules, and removal of extractables and leachables. Tapered pores result in increased thermodynamic and kinetic properties for both adsorption and desorption. The Carboxens vary in the relative percentage of pore structures (micro, meso, and macro), surface area, and surface pH.

Features and Benefits

Features and Benefits:

  • Spherical
  • Hard (ball pan hardness >98%)
  • Stable up to 400°C
  • High purity
  • Easy to pack
  • Stable over entire pH range
  • Do not create backpressure
  • High osmotic shock stability
  • Tapered pore sizing (from macro- to meso- to micro-)

Other Notes

For more information, please visit: specialty Carbon Adsorbents

Legal Information

Carboxen is a registered trademark of Merck KGaA, Darmstadt, Germany

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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The effects of temperature and pressure on the performance of Carboxen/PDMS fibres during solid phase microextraction (SPME) of headspace volatiles from cooked and raw turkey breast.
Brunton NP, et al.
Flavour and Fragrance Journal, 16(4), 294-302 (2001)
RSC Chromatography Monographs
Pawliszyn J. et al.
Applications of Solid Phase Microextraction, 64-65 (1999)
S W Jenkins et al.
Environmental science and pollution research international, 2(4), 207-210 (1995-07-01)
A simple, rapid method for the extraction of N-nitrosodimethylamine (NDMA) from drinking and surface waters was developed using Ambersorb 572. Development of an alternative method to classical liquid-liquid extraction techniques was necessary to handle the workload presented by implementation of
Frank Sporkert et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 772(1), 45-51 (2002-05-23)
A new and in part automated headspace solid-phase microextraction method for quantitative determination of the highly toxic rodenticide fluoroacetic acid (FAA) in serum and other biological samples has been developed. FAA and deuterated acetic acid (internal standard) were extracted from
Filippo Maggi et al.
Chemistry & biodiversity, 8(1), 95-114 (2011-01-25)
Headspace solid-phase microextraction (HS-SPME) coupled with GC/FID and GC/MS was applied for the first time in the analysis of the volatile fraction of an Ephedra species. Notably, six Italian populations (Marche, Abruzzo, and Sardinia) of Ephedra nebrodensis subsp. nebrodensis, covering

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