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Key Documents

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Safety Information

Z2125

Sigma-Aldrich

Zearalenone

fungal mycotoxin

Synonym(s):

F-2 toxin

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5 G
CN¥508.18
25 G
CN¥2,645.56
50 G
CN¥4,603.87

CN¥508.18

List PriceCN¥846.97Save 40%

Available to ship onApril 17, 2025Details

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5 G
CN¥508.18
25 G
CN¥2,645.56
50 G
CN¥4,603.87

About This Item

Empirical Formula (Hill Notation):
C18H22O5
CAS Number:
17924-92-4
Molecular Weight:
318.36
Beilstein:
1350216
MDL number:
MFCD00133085
UNSPSC Code:
12191503
PubChem Substance ID:
24902175
NACRES:
NA.77

CN¥508.18

List PriceCN¥846.97Save 40%

Available to ship onApril 17, 2025Details

Request a Bulk Order

Quality Level

300

storage temp.

−20°C

SMILES string

C[C@H]1CCCC(=O)CCC\C=C\c2cc(O)cc(O)c2C(=O)O1

InChI

1S/C18H22O5/c1-12-6-5-9-14(19)8-4-2-3-7-13-10-15(20)11-16(21)17(13)18(22)23-12/h3,7,10-12,20-21H,2,4-6,8-9H2,1H3/b7-3+/t12-/m0/s1

InChI key

MBMQEIFVQACCCH-QBODLPLBSA-N

Gene Information

mouse ... Esr1(13982)

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Show Differences

1 of 4

This Item
M744432939322327
Zearalenone fungal mycotoxin

Z2125

Zearalenone

Maurotoxin recombinant, expressed in E. coli, ≥95% (HPLC), lyophilized powder

M7444

Maurotoxin

Zearalenone reference material

32939

Zearalenone

Diphtheria Toxin, CRM Mutant Diphtheria Toxin, CRM197 Mutant, CAS 92092-36-9, is a nontoxic material with a glycine to glutamic acid mutation at amino acid 52 in fragment A, resulting in the complete loss of enzymatic activity.

322327

Diphtheria Toxin, CRM Mutant

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

2-8°C

Gene Information

mouse ... Esr1(13982)

Gene Information

-

Gene Information

-

Gene Information

-

Biochem/physiol Actions

Zearalenone, a fungal mycotoxin produced by Fusarium, binds the estrogen receptor (ER) and is uterotropic in the newborn rat. It is a common contaminant in cereal grain used for animal and human food, and exerts an estrogenic activity that modulates/disrupts endocrine function in animals and possibly humans.[1]

Pictograms

Health hazardCorrosion
GHS08,GHS05

Signal Word

Danger

Hazard Statements

H314,H361d

Hazard Classifications

Eye Dam. 1 - Repr. 2 - Skin Corr. 1B

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

高风险级别生物产品--毒素类产品
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    Certificates of Analysis (COA)

    Lot/Batch Number
    0000400767
    0000400767
    0000389387
    0000371487
    0000334571

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    Katarzyna Cieplińska et al.
    Toxins, 11(5) (2019-05-30)
    Zearalenone is a frequent contaminant of cereals and their by-products in regions with a temperate climate. This toxic molecule is produced naturally by Fusarium fungi in crops. The aim of this study was to determine the influence of low zearalenone
    D M Sheehan et al.
    Teratology, 29(3), 383-392 (1984-06-01)
    Fusarium sp. contaminated feedstuffs elicit adverse estrogenic effects in several commercially important animal species via the mycotoxin zearalenone. An estrogenically active synthetic derivative, zearalanol, is used as an anabolic agent in cattle. Since estrogens can irreversibly alter target tissue development
    H Leffers et al.
    Human reproduction (Oxford, England), 16(5), 1037-1045 (2001-05-02)
    We have compared the oestrogenic potency of the synthetic oestrogen Zeranol, used as a growth promoter in meat production, and five related compounds, with the potency of 17beta-oestradiol, diethylstilboestrol (DES), genistein, and Bisphenol-A. The potency was assayed by analysing differences
    Zearalenone and zeranol: potential residue problems in livestock.
    S F Sundlof et al.
    Veterinary and human toxicology, 28(3), 242-250 (1986-06-01)
    Yu Tian et al.
    Theranostics, 11(11), 5197-5213 (2021-04-17)
    Rationale: Zearalenone (ZEN), a pollutant in our daily diet, seriously threatens the reproductive health of humans and animals. The primordial follicle (PF) assembly in the mouse occurs during the perinatal period, which determines the whole ovarian reserve in reproductive lifespan.
    View All Related Papers

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