X1126
Xylazine
≥99%
Synonym(s):
2-(2,6-Dimethylphenylamino)-5,6-dihydro-4H-thiazine
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About This Item
Empirical Formula (Hill Notation):
C12H16N2S
CAS Number:
Molecular Weight:
220.33
EC Number:
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
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Quality Level
Assay
≥99%
storage temp.
−20°C
SMILES string
Cc1cccc(C)c1NC2=NCCCS2
InChI
1S/C12H16N2S/c1-9-5-3-6-10(2)11(9)14-12-13-7-4-8-15-12/h3,5-6H,4,7-8H2,1-2H3,(H,13,14)
InChI key
BPICBUSOMSTKRF-UHFFFAOYSA-N
General description
Xylazine is soluble in methanol (50 mg/ml), yielding a clear, colorless solution. It is also soluble in dilute HCl acid and in chloroform. Xylazine is practically insoluble in water and in alkali solutions.
Application
Xylazine has been used to anaesthetise experimental animals.
Biochem/physiol Actions
Xylazine when used along with ketamine is considered to be a potent and safe anaesthetic in experimental animal. It is known to elevate the hepatic release of glucose, which aggravates to hyperglycemia.
α2-adrenoceptor agonist, sedative, muscle relaxant.
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 3 Oral
Storage Class Code
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
监管及禁止进口产品
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Effect of xylazine on plasma glucose, glucagon and insulin concentrations in sheep
Brockman, RP
Research in Veterinary Science, 30(3), 383-384 (1981)
Lactobacillus casei addition to a repletion diet-induced early normalisation of cytokine profils during a pneumococcal infection in malnourished mice
Salva S, et al.
Food and agricultural immunology, 19(3), 195-211 (2008)
Acute reversible cataract induced by xylazine and by ketamine-xylazine anesthesia in rats and mice
Calderone L, et al.
Experimental Eye Research, 42(4), 331-337 (1986)
MIND model for triple-negative breast cancer in syngeneic mice for quick and sequential progression analysis of lung metastasis
Ghosh A, et al.
PLoS ONE, 13(5), e0198143-e0198143 (2018)
Imaging of rat optic nerve axons in vivo
Koch JC, et al.
Nature Protocols, 6(12), 1887-1887 (2011)
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