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W0270

Sigma-Aldrich

WAY 161503 hydrochloride

≥98% (HPLC)

Synonym(s):

8,9-Dichloro-2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5(6H)-one hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C11H11Cl2N3O · HCl
CAS Number:
276695-22-8
Molecular Weight:
308.59
MDL number:
MFCD06411596
UNSPSC Code:
12352202
PubChem Substance ID:
329830422
NACRES:
NA.77

Quality Level

100

Assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to off-white

solubility

DMSO: >10 mg/mL

originator

Wyeth

storage temp.

room temp

SMILES string

Cl.Clc1cc2NC(=O)C3CNCCN3c2cc1Cl

InChI

1S/C11H11Cl2N3O.ClH/c12-6-3-8-9(4-7(6)13)16-2-1-14-5-10(16)11(17)15-8;/h3-4,10,14H,1-2,5H2,(H,15,17);1H

InChI key

YPNWSZJDAKOUAW-UHFFFAOYSA-N

Biochem/physiol Actions

The 5-HT2C receptors have been implicated in conditions including obesity, anxiety, depression, OCD, schizophrenia, migraine, nociception and erectile dysfunction.

Features and Benefits

This compound was developed by Wyeth. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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Adam L Halberstadt et al.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 34(8), 1958-1967 (2009-03-27)
Although it is well established that hallucinogens act as 5-HT(2A) and 5-HT(2C) receptor agonists, little is known about the relative contributions of 5-HT(2A) and 5-HT(2C) receptors to the acute behavioral effects of these drugs. The behavioral pattern monitor was used

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