V9752
Scorpion venom from Centruroides sculpturatus
Synonym(s):
(Bark Scorpion)
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About This Item
NACRES:
NA.77
UNSPSC Code:
12352200
storage temp.
−20°C
Quality Level
General description
Centruroides sculpturatus scorpion venom induces severe neuromotor disturbance. The venom is composed of prime toxins that target ion-channels especially, the sodium (Na+)-channel.
Scorpion venom are species-specific, which functions in prey capture or predator deterence. It might be lethal to humans. It induces prolonged and excessive firing of neuronal axons, that results in a wide range of signs and symptoms. Scorpion venom might be associated with local pain, bronchoconstriction, neurologic and cardiovascular collapse.
Application
Scorpion venom from Centruroides sculpturatus has been used to activate neuronal sodium channels.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Neural control of the endocrine rat heart
Jiao JH and Baertschi AJ
Proceedings of the National Academy of Sciences of the USA, 90(16), 7799-7803 (1993)
Norma A Valdez-Cruz et al.
Biochimie, 86(6), 387-396 (2004-09-11)
Current literature concerning the taxonomic names of two possibly distinct species of scorpions from the genus Centruroides (sculpturatus and/or exilicauda) is controversial. This communication reports the results of biochemical, genetic and electrophysiological experiments conducted with C. exilicauda Wood of Baja
Intraspecific variation of Centruroides sculpturatus scorpion venom from two regions of Arizona
Carcamo-Noriega EN, et al.
Archives of Biochemistry and Biophysics, 638, 52-57 (2018)
Stephen A Klotz et al.
The American journal of medicine, 134(8), 1034-1038 (2021-02-26)
Arizona's rugged desert landscape harbors many venomous animals, including a small nocturnal scorpion, Centruroides sculpturatus, whose venom can cause severe neuromotor disturbance. An effective antivenom is available at selected health care facilities in the state. We analyzed 4398 calls of
Envenomation by the scorpion Centruroides sculpturatus
Curry SC, et al.
Journal of Toxicology: Clinical Toxicology, 21(4-5), 417-449 (1983)
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