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V6627

Anti-Vascular Endothelial Growth Factor antibody produced in goat

IgG fraction of antiserum, lyophilized powder

Synonym(s):

Anti-VEGF

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
MDL number:
MFCD00282511

Key Documents

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Product Name

Anti-Vascular Endothelial Growth Factor antibody produced in goat, IgG fraction of antiserum, lyophilized powder

biological source

goat

conjugate

unconjugated

antibody form

IgG fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

form

lyophilized powder

species reactivity

human

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 5-15 μg/mL
neutralization: suitable
western blot: 1-2 μg/mL

UniProt accession no.

P15692

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

200

Gene Information

human ... VEGFA(7422)

Biochem/physiol Actions

The antibody will neutralize the biological activity of recombinant human VEGF165 and recombinant human VEGF121. The antibody shows ~20% cross-reactivity with recombinant mouse VEGF and recombinant rat VEGF.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Immunogen

recombinant human VEGF.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing carbohydrates.

Preparation Note

Purified using protein G.

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
MKCR2770
MKCC9241
MKBW1439V
SLBD2884V
SLBC7131V

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Jertta-Riina Sarkanen et al.
Frontiers in pharmacology, 1, 147-147 (2010-01-01)
The developed standardized human cell based in vitro angiogenesis assay was intra-laboratory pre-validated to verify that the method is reliable and relevant for routine testing of modulators of angiogenesis, e.g., pharmaceuticals and industrial chemicals. This assay is based on the
Markus Theurl et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 32(9), 4815-4823 (2018-06-20)
The pathogenesis of diabetic neuropathy remains enigmatic. Damage to the vasa nervorum may be responsible for this disorder. Recently, we showed that secretoneurin (SN) induces angiogenesis in hindlimb and myocardial ischemia. Moreover, beneficial effects were observed in wound healing. We
Ilnur I Salafutdinov et al.
Biomedicines, 11(7) (2023-07-29)
The biosafety of gene therapy remains a crucial issue for both the direct and cell-mediated delivery of recombinant cDNA encoding biologically active molecules for the pathogenetic correction of congenital or acquired disorders. The diversity of vector systems and cell carriers
Laijian Sui et al.
Frontiers in cell and developmental biology, 12, 1374269-1374269 (2024-08-05)
The present study aimed to investigate the involvement of aberrant BMP8A expression in TNBC and bone metastasis. Aberrant expression of BMP8A in breast cancer was first determined by analyzing The Cancer Genome Atlas breast cancer cohort (TCGA-BRCA) and an immunohistochemical
Henning Ulrich et al.
Frontiers in pharmacology, 9, 500-500 (2018-06-06)
Bone marrow metastasis occurs in approximately 350,000 patients that annually die in the U.S. alone. In view of the importance of tumor cell migration into the bone marrow, we have here investigated effects of various concentrations of stromal cell-derived factor-1
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Data Sheet - V6627

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