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V5626

Sigma-Aldrich

Val-Tyr

>98% (TLC), suitable for ligand binding assays

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About This Item

Empirical Formula (Hill Notation):
C14H20N2O4
CAS Number:
Molecular Weight:
280.32
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.26

Product Name

Val-Tyr,

Assay

>98% (TLC)

form

powder

technique(s)

ligand binding assay: suitable

color

white to off-white

storage temp.

−20°C

SMILES string

OC([C@@H](NC([C@@H](N)C(C)C)=O)CC1=CC=C(O)C=C1)=O

InChI

1S/C14H20N2O4/c1-8(2)12(15)13(18)16-11(14(19)20)7-9-3-5-10(17)6-4-9/h3-6,8,11-12,17H,7,15H2,1-2H3,(H,16,18)(H,19,20)

InChI key

VEYJKJORLPYVLO-UHFFFAOYSA-N

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Mitsuru Tanaka et al.
Bioscience, biotechnology, and biochemistry, 70(9), 2292-2295 (2006-09-09)
In this study, we found that antihypertensive di-peptide Val-Tyr (VY) showed a vascular relaxation effect in KCl-induced contraction of thoracic aorta rings from 18-week-old spontaneously hypertensive rats among di-peptides of VY, Ile-Tyr, and Tyr-Val irrespective of their angiotensin I-converting enzyme
Takao Ueno et al.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 21(8), 997-1000 (2005-08-27)
A double column-switching HPLC method with naphthalene-2,3-dialdehyde (NDA) was applied for determination of two plasma antihypertensive peptides, Val-Tyr (VY) and Ile-Val-Tyr (IVY). After a first separation on a Phe-ODS column, double heart-cuts of the retention time corresponding to NDA-VY and
Jocksan I Morales-Camacho et al.
Applied microbiology and biotechnology (2018-09-14)
The insertion of peptides is a biotechnology tool widely used to improve the nutraceutical properties of proteins. Because the effect of these insertions in protein stability and function is difficult to predict, it should be determined experimentally. In this study
Toshiro Matsui et al.
Life sciences, 79(26), 2492-2498 (2006-09-09)
Some di-peptides have been proven to exert an antihypertensive effect in mild-hypertensive subjects. The aim of this study was to clarify whether combined administration of an ACE inhibitor, captopril, with an antihypertensive di-peptide Val-Tyr (VY) would alter their potent antihypertensive
Spectroscopic and structural elucidation of L-tyrosine-containing dipeptides valyl-tyrosine and tyrosyl-alanine: solid-state IR-LD spectroscopy, quantum chemical calculations and vibrational analysis.
Koleva BB, Kolev TM, Spiteller M.
Spectrochimica Acta Part A: Molecular Spectroscopy, 68, 1187-1196 (2007)

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