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Biochem/physiol Actions
Snake venom from Bothrops jararaca mainly contains three types of toxins snake venom metalloproteinases (SVMP), snake venom serine proteases (SVSP), and C-type lectin-like proteins (CTLP). These toxins aids in the pathogenesis of envenomation by activating blood coagulation prothrombin, von Willebrand factor (VWF), and factor X, and by altering the function of protein C, kininogen, and blood platelets.
WGK
WGK 3
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Not applicable
Flash Point(C)
Not applicable
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dust mask type N95 (US), Eyeshields, Gloves
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Júlia Morais Fernandes et al.
PloS one, 11(12), e0168658-e0168658 (2016-12-30)
The species Kalanchoe brasiliensis and Kalanchoe pinnata, both known popularly as "Saião," are used interchangeably in traditional medicine for their antiophidic properties. Studies evaluating the anti-venom activity of these species are scarce. This study aims to characterize the chemical constituents
K M Brinkhous et al.
Proceedings of the National Academy of Sciences of the United States of America, 80(5), 1463-1466 (1983-03-01)
Botrocetin, originally called venom coagglutinin, is a Bothrops factor that causes aggregation of blood platelets in the presence of the von Willebrand component of the factor VIII macromolecular complex. The complex consists of a series of multimers with a molecular
Aqueous leaf extract of Jatropha mollissima (Pohl) Bail decreases local effects induced by bothropic venom
Gomes Jacyra Antunes dos S, et al.
BioMed Research International, 2016, e0160638-e0160638 (2016)
Glutamate receptor interacting protein 1 mediates platelet adhesion and thrombus formation
Modjeski KL, et al.
PLoS ONE, 11(9), e0160638-e0160638 (2016)
Camila Martos Thomazini et al.
PLoS neglected tropical diseases, 15(9), e0009715-e0009715 (2021-09-04)
Patients bitten by snakes consistently manifest a bleeding tendency, in which thrombocytopenia, consumption coagulopathy, mucous bleeding, and, more rarely, thrombotic microangiopathy, are observed. Von Willebrand factor (VWF) is required for primary hemostasis, and some venom proteins, such as botrocetin (a
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