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V3138

Sigma-Aldrich

D-Val-Leu-Lys 7-amido-4-methylcoumarin

≥98% (HPLC), lyophilized powder

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MDL number:
MFCD00038828
UNSPSC Code:
12352204
PubChem Substance ID:
329829038
NACRES:
NA.32

Quality Level

200

Assay

≥98% (HPLC)

form

lyophilized powder

mol wt

apparent mol wt 744

solubility

0.1% trifluoroacetic acid in acetonitrile: water (3:1): 1 mg/mL, clear, colorless

storage temp.

−20°C

SMILES string

CC(C)C[C@H](NC(=O)[C@H](N)C(C)C)C(=O)N[C@@H](CCCCN)C(=O)Nc1ccc2C(C)=CC(=O)Oc2c1

InChI

1S/C27H41N5O5/c1-15(2)12-21(32-27(36)24(29)16(3)4)26(35)31-20(8-6-7-11-28)25(34)30-18-9-10-19-17(5)13-23(33)37-22(19)14-18/h9-10,13-16,20-21,24H,6-8,11-12,28-29H2,1-5H3,(H,30,34)(H,31,35)(H,32,36)/t20-,21-,24+/m0/s1

InChI key

NMAUGTNXBOFHCJ-AWRGLXIESA-N

Biochem/physiol Actions

Plasmin, tissue plasminogen activator substrate

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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M S Baker et al.
Biochimica et biophysica acta, 1117(2), 143-152 (1992-09-15)
The development of a simple, sensitive fluorimetric assay for the measurement of cell surface-associated urokinase plasminogen activator (uPA) on viable, adherent HCT116 cells in microtitre plates, after a preincubation with purified human plasminogen is described. The assay determines plasmin activity

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