V2889
Valeryl Salicylate
≥98% (HPLC)
Synonym(s):
2-Valeryloxybenzoic acid, Valerylsalicylic acid, vsa
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About This Item
Empirical Formula (Hill Notation):
C12H14O4
CAS Number:
Molecular Weight:
222.24
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Product Name
Valeryl Salicylate, ≥98% (HPLC)
InChI key
WJHZBTMHUNVIKC-UHFFFAOYSA-N
SMILES string
CCCCC(=O)Oc1ccccc1C(O)=O
InChI
1S/C12H14O4/c1-2-3-8-11(13)16-10-7-5-4-6-9(10)12(14)15/h4-7H,2-3,8H2,1H3,(H,14,15)
assay
≥98% (HPLC)
form
solid
color
white
mp
86-87 °C (lit.)
solubility
DMSO: 24 mL/mL
H2O: insoluble
Quality Level
Related Categories
Biochem/physiol Actions
Selective, irreversible COX-1 inhibitor. The selectivity for COX-1 vs COX-2 shows the IC50 values for ovine COX-1 vs COX-2 of 0.8 μM vs. 15 mM respectively.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
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Augmented endothelium-dependent contractions (EDC) contributes to endothelial dysfunction and vascular disease progression. An early signal in EDC is cytosolic [Ca2+]i rise in endothelial cells, which stimulates the production of contractile prostanoids, leading to vascular contraction. In this study, the molecular
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