Skip to Content
Merck
CN

U3128

Uroporphyrin I dihydrochloride

≥95%

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Empirical Formula (Hill Notation):
C40H38N4O16 · 2HCl
CAS Number:
68929-06-6
Molecular Weight:
903.67
NACRES:
NA.22
PubChem Substance ID:
329827626
UNSPSC Code:
12352300
EC Number:
273-038-0
MDL number:
MFCD00058110

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

InChI key

DZLKLVAJOHLPKP-ARSPAUKVSA-N

InChI

1S/C40H38N4O16.2ClH/c45-33(46)5-1-17-21(9-37(53)54)29-14-26-19(3-7-35(49)50)23(11-39(57)58)31(43-26)16-28-20(4-8-36(51)52)24(12-40(59)60)32(44-28)15-27-18(2-6-34(47)48)22(10-38(55)56)30(42-27)13-25(17)41-29;;/h13-16,41,44H,1-12H2,(H,45,46)(H,47,48)(H,49,50)(H,51,52)(H,53,54)(H,55,56)(H,57,58)(H,59,60);2*1H/b25-13-,26-14-,27-15-,28-16-,29-14-,30-13-,31-16-,32-15-;;

SMILES string

Cl.Cl.OC(=O)CCc1c(CC(O)=O)c2cc3[nH]c(cc4nc(cc5[nH]c(cc1n2)c(CC(O)=O)c5CCC(O)=O)c(CC(O)=O)c4CCC(O)=O)c(CC(O)=O)c3CCC(O)=O

assay

≥95%

form

powder

reaction suitability

core: porphyrin, reagent type: catalyst

storage temp.

−20°C

Preparation Note

Enzymatically prepared

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
MKCN3317
MKCM3677
MKCD2958
MKBZ6849V
MKBW6797V

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

S G Afonso et al.
The international journal of biochemistry & cell biology, 28(4), 415-420 (1996-04-01)
Aerobic and anaerobic studies have demonstrated that uroporphyrin I-induced inactivation of delta-aminolevulinic acid dehydratase, porphobilinogenase, deaminase and uroporphyrinogen decarboxylase was dependent on oxygen and mediated by reactive oxygen species. The mechanism of photoinactivation of those heme-enzymes from human erythrocytes by
S G Afonso et al.
The International journal of biochemistry, 26(2), 255-258 (1994-02-01)
1. The action of uroporphyrin I on erythrocytic ALA-D activity under dark and light conditions was examined. 2. Photo and non-photoinactivation of ALA-D induced by uroporphyrin I were observed. 3. Both effects were dependent on uroporphyrin concentration, temperature and time
[Clinical cases in medical mycology. Case no. 20].
Ricardo Negroni et al.
Revista iberoamericana de micologia, 23(2), 116-118 (2006-07-21)
C Ged et al.
Prenatal diagnosis, 16(1), 83-86 (1996-01-01)
Identification of uroporphyrinogen III synthase (UROIIIS) gene mutations in patients with congenital erythropoietic porphyria (CEP) allows fast and reliable carrier detection and prenatal diagnosis. We describe here the first case of prenatal diagnosis by concomitant measurement of uroporphyrin I in
Kenzi Nakano et al.
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, 22(2), 345-351 (2008-10-29)
Accumulating evidence, including experiments using cytochrome P450 1a2 (Cyp1a2) gene knock-out mice (Cyp1a2(-/-)), indicates that the development of chemically induced porphyria requires the expression of CYP1A2. It has also been demonstrated that iron enhances and expedites the development of experimental
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service