T8753
2-(p-Toluidino)-6-naphthalenesulfonic acid potassium salt
suitable for fluorescence, BioReagent
Synonym(s):
TNS
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About This Item
Linear Formula:
C17H14NO3SK
CAS Number:
Molecular Weight:
351.46
UNSPSC Code:
12352200
PubChem Substance ID:
EC Number:
251-196-1
MDL number:
SMILES string
[K+].Cc1ccc(Nc2ccc3cc(ccc3c2)S([O-])(=O)=O)cc1
product line
BioReagent
suitability
suitable for fluorescence
storage temp.
2-8°C
Application
Fluorescent probe for the conformational state of proteins.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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S Shankara Narayanan et al.
Langmuir : the ACS journal of surfaces and colloids, 23(12), 6712-6718 (2007-05-04)
In this contribution, we report studies on nonspecific protein-DNA interactions of an enzyme protein bovine pancreatic alpha-chymotrypsin (CHT) with genomic DNA (from salmon testes) using two biologically common fluorescent probes: 1-anilinonaphthalene-8-sulfonate (ANS) and 2,6-p-toluidinonaphthalene sulfonate (TNS). TNS molecules that are
Ilona Fitos et al.
Biochimica et biophysica acta, 1760(11), 1704-1712 (2006-09-30)
Imatinib is a selective tyrosine kinase inhibitor, successfully used for the treatment of chronic myelogenous leukaemia. Its strong plasma protein binding referred to alpha1-acid glycoprotein (AGP) component was found to inhibit the pharmacological activity. AGP shows genetic polymorphism and the
Zhi-Jun Wang et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 70(4), 892-897 (2007-12-07)
The interaction between 2-p-toluidinylnaphthalene-6-sulfonate (TNS) and ciliate Euplotes Octocarinatus centrin (Cen) has been studied by fluorescence spectroscopy. The binding constants of TNS with Cen were measured at different temperature in the 0.01M Hepes, pH 7.4. The binding process is exothermic
Guoting Li et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 67(5), 1189-1193 (2006-11-28)
Glu is highly conserved as the first amino acid of E-helix of the EF-hand protein. In this paper, Glu 101, the first amino acid of E-helix of the third EF-hand motif in Euplotes octocarinatus centrin (EoCen) was mutated to be
Atya Aziz et al.
Biochemistry, 46(9), 2510-2519 (2007-02-07)
This study aimed to study the oligomeric size, structure, hydrodynamic properties, and chaperone function of the C-terminally truncated human alphaA-crystallin mutants with special emphasis on alphaA1-172 which is the cleavage product of the Ser172-Ser173 bond, unique to human lenses and
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