T7063
Tryptase from human lung
buffered aqueous solution, ≥5 units/mg protein
Synonym(s):
Tryptase enzyme
About This Item
form
buffered aqueous solution
Quality Level
specific activity
≥5 units/mg protein
mol wt
~135 kDa
shipped in
dry ice
storage temp.
−20°C
Gene Information
human ... TPSAB1(7177) , TPSB2(64499) , TPSD1(23430) , TPSG1(25823)
General description
Application
Biochem/physiol Actions
Tryptase is released from the mast cell as a result of the degranulation response during anaphylaxis. In addition, several tryptase genes and alleles (α, β, γ & δ) have been identified in various tissues and circulating in blood. Pro-β-tryptase is thought to be the constituative circulating form in blood.
The biological function of tryptase is unknown. However it has been reported to catalyze the activation of complement C3, convert prostromelysin to stromelysin (MMP-3), and cleave fibrinogen resulting in a loss of clottting potential. Tryptase also degrades fibronectin, calcitonin gene-related peptide, vasoactive intestinal peptide,
and kininogen.
Quality
Physical properties
Unit Definition
Physical form
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
Certificates of Analysis (COA)
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If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.
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What is the extinction coefficient (E1%) of product T7063, Tryptase from human lung?
The extinction coefficient (E1%) of product T7063, Tryptase from human lung, is 30.3 when measured at 280 nm wavelength.
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