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Key Documents

Safety Information

T6830

Sigma-Aldrich

Thyroglobulin human

Synonym(s):

Thyroglobulin human

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30 ML
CN¥5,619.29

CN¥5,619.29

Available to ship onApril 24, 2025Details

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30 ML
CN¥5,619.29

About This Item

CAS Number:
9010-34-8
EC Number:
232-721-3
MDL number:
MFCD01324794
UNSPSC Code:
12352202
NACRES:
NA.56

CN¥5,619.29

Available to ship onApril 24, 2025Details

Request a Bulk Order

biological source

human

Quality Level

200

Assay

≥95% (SDS-PAGE)

form

lyophilized solid

technique(s)

cell culture | mammalian: suitable

UniProt accession no.

P01266

storage temp.

2-8°C

Gene Information

human ... TG(7038)

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Show Differences

1 of 4

This Item
50208U50197U50193U
Partisil™ 5 ODS3 HPLC Column 5 μm particle size, L × I.D. 10 cm × 4.6 mm

50204U

Partisil™ 5 ODS3 HPLC Column

Partisil™ 5 ODS HPLC Column phase C18 (octadecyl), 5 μm particle size, L × I.D. 25 cc × 4.6 mm

50208U

Partisil™ 5 ODS HPLC Column

Partisil™ 10 SCX HPLC Column 10 μm particle size, L × I.D. 25 cm × 4.6 mm

50197U

Partisil™ 10 SCX HPLC Column

Partisil™ 10 SAX HPLC Column pore size 85 Å, 10 μm particle size, L × I.D. 25 cm × 4.6 mm

50193U

Partisil™ 10 SAX HPLC Column

matrix

octadecyl

matrix

octadecyl

matrix

sulphonic acid

matrix

tetramethyl ammonium

separation technique

reversed phase

separation technique

reversed phase

separation technique

cation exchange

separation technique

anion exchange

matrix active group

C18 (octadecyl) phase

matrix active group

C18 (octadecyl) phase

matrix active group

sulfonic acid phase

matrix active group

ammonium ion, quaternary phase

technique(s)

HPLC: suitable

technique(s)

HPLC: suitable

technique(s)

HPLC: suitable

technique(s)

HPLC: suitable

pore size

85 Å

pore size

85 Å

pore size

85 Å

pore size

85 Å

General description

Human Thyroglobulin (Tg) is a 660 kDa, dimeric protein produced by and used entirely within the thyroid gland. Human Thyroglobin is used by the thyroid gland to produce the thyroid hormones thyroxine (T4) and triiodothyryonine. Patients with Hashimoto′s thyroiditis or Graves′ disease, frequently develop antibodies against human Thyroglobulin. Thryoglobulin levels in the blood can be used as a tumor marker for certain kinds of thyroid cancer and in Graves′ disease.

Biochem/physiol Actions

Thyroglobulin has been shown to induce expression of platelet activating factor in human peripheral blood mononuclear cells which is found elevated in some patients with thyroid disease. [1]

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

监管及禁止进口产品
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    Certificates of Analysis (COA)

    Lot/Batch Number
    0000322045
    0000322044
    0000322045
    0000322044
    0000253556

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    E Resetkova et al.
    Regional immunology, 4(4), 204-208 (1992-07-01)
    Platelet activating factor (PAF), a phospholipid mediator, has been found to play a role in immune reactions, as well as in many pathophysiological alterations in certain disorders. To determine whether there might be a potential role of PAF in the
    Ricardo Adaixo et al.
    Nature communications, 13(1), 61-61 (2022-01-12)
    The thyroglobulin (TG) protein is essential to thyroid hormone synthesis, plays a vital role in the regulation of metabolism, development and growth and serves as intraglandular iodine storage. Its architecture is conserved among vertebrates. Synthesis of triiodothyronine (T3) and thyroxine
    Elgin Ozkan et al.
    Clinical nuclear medicine, 38(5), 326-331 (2013-03-15)
    This study aimed to investigate the correlation of 18F-FDG PET/CT findings with histopathological results in defining the recurrence of the disease in patients with differentiated thyroid cancer (DTC) who have increased thyroglobuline (Tg) or anti-Tg antibody (TgAb) levels and negative
    Pengfei Zhang et al.
    Nature communications, 13(1), 2298-2298 (2022-04-29)
    Evanescent illumination has been widely used to detect single biological macromolecules because it can notably enhance light-analyte interaction. However, the current evanescent single-molecule detection system usually requires specially designed microspheres or nanomaterials. Here we show that single protein detection and
    Mark M Kushnir et al.
    Clinical chemistry, 59(6), 982-990 (2013-02-12)
    Measurement of serum thyroglobulin (Tg) is used to monitor patients after treatment for differentiated thyroid carcinoma (TC). Difficulty in using Tg as a biomarker of the recurrence of TC in many patients stems from the presence of endogenous anti-Tg autoantibodies
    View All Related Papers

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