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T6205

Sigma-Aldrich

TPh A

≥98% (HPLC)

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Synonym(s):
N-{[4-(Benzyloxy)phenyl](methyl)-γ4-sulfanylidene}-4-methylbenzenesulfonamide, S-[p-(Benzyloxy)phenyl]-S-methyl-N-(p-tolylsulfonyl)-sulfilimine, Triphenyl compound A
Empirical Formula (Hill Notation):
C21H21NO3S2
CAS Number:
Molecular Weight:
399.53
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:

Assay

≥98% (HPLC)

form

powder

color

white

solubility

DMSO: >30 mg/mL

storage temp.

2-8°C

SMILES string

Cc1ccc(cc1)S(=O)(=O)N=S(C)c2ccc(OCc3ccccc3)cc2

InChI

1S/C21H21NO3S2/c1-17-8-14-21(15-9-17)27(23,24)22-26(2)20-12-10-19(11-13-20)25-16-18-6-4-3-5-7-18/h3-15H,16H2,1-2H3

InChI key

IMUPOWQOXOCVBN-UHFFFAOYSA-N

Biochem/physiol Actions

TPh A is an inhibitor of the nuclear protein pirin. TPh A (Triphenyl compound A) inhibits the interaction between Bcl3 oncoprotein and the nuclear protein pirin. TPh A inihibits melanoma cell migration.

Preparation Note

TPh A is soluble in DMSO at a concentration that is greater than 30 mg/ml.

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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