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T5691

Sigma-Aldrich

TES

BioPerformance Certified, suitable for cell culture, ≥99% (titration)

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Synonym(s):
2-[(2-Hydroxy-1,1-bis(hydroxymethyl)ethyl)amino]ethanesulfonic acid, N-[Tris(hydroxymethyl)methyl]-2-aminoethanesulfonic acid, TES free acid
Empirical Formula (Hill Notation):
C6H15NO6S
CAS Number:
7365-44-8
Molecular Weight:
229.25
Beilstein:
1957061
EC Number:
230-906-3
MDL number:
MFCD00007532
UNSPSC Code:
12161700
PubChem Substance ID:
24900309
NACRES:
NA.25

grade

BioPerformance Certified

Assay

≥99% (titration)

form

crystalline powder

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin and total aerobic microbial count, tested

useful pH range

6.8-8.2

pKa (25 °C)

7.5

mp

~225 °C (dec.)

solubility

H2O: 25 g plus 50 mL, clear, colorless

cation traces

heavy metals (as Pb): ≤5 ppm

application(s)

diagnostic assay manufacturing

foreign activity

DNase, RNase, Nickase and protease, none detected

SMILES string

OCC(CO)(CO)NCCS(O)(=O)=O

InChI

1S/C6H15NO6S/c8-3-6(4-9,5-10)7-1-2-14(11,12)13/h7-10H,1-5H2,(H,11,12,13)

InChI key

JOCBASBOOFNAJA-UHFFFAOYSA-N

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WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Ian Ackers et al.
Frontiers in cardiovascular medicine, 7, 567837-567837 (2020-12-18)
The pathogenesis of atherosclerosis is complex, evolves, and involves many cell types. Macrophages and vascular smooth muscle cells (VSMCs) are critically involved in atherosclerosis development and progression. Several studies have shown that WNT5A protein is abundantly expressed in human atherosclerotic
W J Holmgren et al.
Journal of in vitro fertilization and embryo transfer : IVF, 6(4), 207-212 (1989-08-01)
Penetration of zona-free hamster oocytes by human spermatozoa after preincubation with BWW medium (standard technique) or a buffer system containing egg yolk (TESTY) was compared by applying both treatments to aliquots of 60 ejaculates from 34 patients. The TESTY-treated spermatozoa
N Sugiyama et al.
Molecular reproduction and development, 58(1), 30-38 (2001-01-06)
The growth, differentiation, and death/survival of spermatogonia are precisely regulated for the proper production of spermatozoa. We have previously shown that Bcl-2 ectopically expressed in spermatogonia caused the inhibition of normal spermatogonial apoptosis and the subsequent failure of differentiation in
R H Martin et al.
Biology of reproduction, 47(2), 268-270 (1992-08-01)
Human sperm karyotypes can be prepared after fusion of human sperm with Golden hamster oocytes. Most laboratories use one of two methods of sperm capacitation: incubation of freshly-ejaculated sperm in Biggers, Whitten, and Whittingham (BWW) medium for 5-7 h at
G M Randall et al.
Gastroenterology, 96(5 Pt 1), 1274-1281 (1989-05-01)
Excellent clinical results have been reported with sclerotherapy for control of nonvariceal gastrointestinal hemorrhage. However, there are few controlled or comparative data on different sclerosing agents for treatment of lesions with active arterial bleeding or nonbleeding visible vessels. In a
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