Skip to Content
Merck
CN
All Photos(2)

Documents

T4446

SAFC

N-Acetyl-L-tyrosine

Sign Into View Organizational & Contract Pricing
All Photos(2)
Linear Formula:
4-(HO)C6H4CH2CH(NHCOCH3)CO2H
CAS Number:
537-55-3
Molecular Weight:
223.23
Beilstein:
2697172
EC Number:
208-671-3
MDL number:
MFCD00037190
UNSPSC Code:
12352209
NACRES:
NA.26

biological source

non-animal source

Assay

≥98.5%

form

crystalline powder

manufacturer/tradename

Ajinomoto

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, heavy metals, tested

mp

149-152 °C (lit.)

solubility

H2O: 25 mg/mL

application(s)

pharmaceutical (small molecule)

SMILES string

CC(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O

InChI

1S/C11H13NO4/c1-7(13)12-10(11(15)16)6-8-2-4-9(14)5-3-8/h2-5,10,14H,6H2,1H3,(H,12,13)(H,15,16)/t10-/m0/s1

InChI key

CAHKINHBCWCHCF-JTQLQIEISA-N

Looking for similar products? Visit Product Comparison Guide

General description

To request documentation for this product, please contact Customer Support and select ‘Product Documentation′. Please note that access to documentation for this product requires a confidentiality disclosure agreement.

Application

L-Tyrosine is a non-essential amino acid. It can be used as a cell culture media component in the commercial biomanufacture of therapeutic recombinant proteins and monoclonal antibodies. N-Acetyl-L-tyrosine is an acetylated derivative of the essential amino acid L-tyrosine with reported improved nutritional properties.

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

[Recording the delta-pH-generating biochemical reactions by light-addressed sensors with Ta2O5 dielectrics].
A N Reshetilov et al.
Doklady Akademii nauk, 342(5), 700-702 (1995-06-01)
Rakesh Kumar et al.
European journal of medicinal chemistry, 42(4), 503-510 (2006-12-26)
The development of type 2 diabetes in obese individuals is linked to lipid accumulation in non-adipose tissues. A series of N-acetyl-L-tyrosine derivatives were synthesized and evaluated for PPAR transactivation. Compounds 4d and 4f were found to show better PPARalpha transactivation
T Nishiyama et al.
Journal of biochemistry, 127(3), 427-433 (2000-03-25)
It was previously revealed [Yamaguchi, H., Nishiyama, T., and Uchida, M. (1999) J. Biochem. 126, 261-265] that N-glycans of both the high-mannose and complex types have binding affinity for aromatic amino acid residues. This study shows that free N-glycans protect
Sandrine Perrier et al.
Journal of the American Chemical Society, 131(34), 12458-12465 (2009-08-08)
Steady-state (1)H photo-chemically induced dynamic nuclear polarization (CIDNP) experiments were conducted at 14.1 T on deoxygenated (buffered pH 7) aqueous solutions of [Ru(phen)(3)](2+), [Ru(tap)(2)(phen)](2+), and [Ru(tap)(3)](2+) (tap = 1,4,5,8-tetraazaphenanthrene; phen = 1,10-phenanthroline) in the presence of guanosine-5'-monophosphate or N-acetyltyrosine. For
A Rescigno et al.
Biochimica et biophysica acta, 1384(2), 268-276 (1998-07-11)
Tyrosinase is a copper containing protein which catalyzes the hydroxylation of monophenols and the oxidation of diphenols to o-quinones. The monophenolase activity of tyrosinase is characterized by a typical lag time. In this paper the influence of 3-hydroxyanthranilic acid on
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service