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T3394

Sigma-Aldrich

Tetraethylene glycol monooctyl ether

liquid, ≥98% (GC)

Synonym(s):

C8E4, Octyl tetraethylene glycol ether, Octyltetraglycol

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About This Item

Linear Formula:
CH3(CH2)7(OCH2CH2)4OH
CAS Number:
Molecular Weight:
306.44
Beilstein:
1781226
MDL number:
UNSPSC Code:
12161900
PubChem Substance ID:
NACRES:
NA.25

description

non-ionic

Quality Level

Assay

≥98% (GC)

form

liquid

mol wt

306.44 g/mol

density

0.969 g/mL at 20 °C (lit.)

SMILES string

CCCCCCCCOCCOCCOCCOCCO

InChI

1S/C16H34O5/c1-2-3-4-5-6-7-9-18-11-13-20-15-16-21-14-12-19-10-8-17/h17H,2-16H2,1H3

InChI key

FEOZZFHAVXYAMB-UHFFFAOYSA-N

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General description

Tetraethylene glycol monooctyl ether is a surfactant.

Application

Reported to be useful in solubilizing membrane proteins.
Tetraethylene glycol monooctyl ether has been used in a study to assess thermal diffusion behavior of nonionic surfactants in water. It has also been used in a study to investigate unusual micelle and surface adsorption behavior in mixtures of surfactants.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Carolanne E Norris et al.
International journal of mass spectrometry, 460 (2020-12-08)
Rhodopsin, a prototypical G-protein-coupled receptor, is responsible for scoptic vision at low-light levels. Although rhodopsin's photoactivation cascade is well understood, it remains unclear how lipid and zinc binding to the receptor are coupled. Using native mass spectrometry, we developed a
Jeremy Guerin et al.
eLife, 9 (2020-10-23)
Bacterial contact-dependent growth inhibition (CDI) systems use a type Vb secretion mechanism to export large CdiA toxins across the outer membrane by dedicated outer membrane transporters called CdiB. Here, we report the first crystal structures of two CdiB transporters from
Raquel Rodríguez-Alonso et al.
Nature chemical biology, 16(9), 1019-1025 (2020-06-24)
The β-barrel assembly machinery (BAM) inserts outer membrane β-barrel proteins (OMPs) in the outer membrane of Gram-negative bacteria. In Enterobacteriacea, BAM also mediates export of the stress sensor lipoprotein RcsF to the cell surface by assembling RcsF-OMP complexes. Here, we
J B Vieira et al.
Langmuir : the ACS journal of surfaces and colloids, 21(10), 4441-4451 (2005-07-22)
Micellization and adsorption at the air-solution interface of binary mixtures of the triblock copolymer of ethylene oxide and propylene oxide, EO23PO52EO23 (EPE), and the surfactants sodium dodecyl sulfate (SDS), dodecyl trimethylammonium chloride (DTAC), and tetraethylene glycol monooctyl ether (C8EO4) have
Christel Le Bon et al.
Nucleic acids research, 42(10), e83-e83 (2014-04-20)
Amphipols (APols) are specially designed amphipathic polymers that stabilize membrane proteins (MPs) in aqueous solutions in the absence of detergent. A8-35, a polyacrylate-based APol, has been grafted with an oligodeoxynucleotide (ODN). The synthesis, purification and properties of the resulting 'OligAPol'

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