T2022
Thyroxine-Binding Globulin from human plasma
buffered aqueous solution
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About This Item
MDL number:
UNSPSC Code:
51111800
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form
buffered aqueous solution
impurities
<0.1 mol/mol protein T4
capacity
≥0.7 mol/mol, protein binding capacity (T4)
UniProt accession no.
storage temp.
2-8°C
Gene Information
human ... SERPINA7(6906)
Physical form
Solution in 0.05 M Tris, pH 8.6, containing 0.25 M NaCl, 0.3 M glycine, and 0.1% sodium azide
Preparation Note
Glycoprotein (54 kDa) produced in the liver and is the primary carrier of thyroxine and triiodothyronine in serum.
Analysis Note
Protein determined by Lowry.
Disclaimer
RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
Regulatory Information
监管及禁止进口产品
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O E Janssen et al.
The Journal of biological chemistry, 267(20), 13998-14004 (1992-07-15)
Thyroxine-binding globulin (TBG) is a glycoprotein that transports thyroid hormones in blood. Of two naturally occurring variants in man that harbor single proline substitutions (TBG-CD5 and TBG-Montreal), only TBG-CD5 manifests as complete TBG deficiency. In order to determine the pathophysiology
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