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T2006

Sigma-Aldrich

L-Tyrosine hydrochloride

≥98% (TLC)

Synonym(s):

3-(4-Hydroxyphenyl)-L-alanine, 3-(4-Hydroxyphenyl)-L-alanine hydrochloride

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About This Item

Linear Formula:
HOC6H4CH2CH(NH2)CO2H·HCl
CAS Number:
16870-43-2
Molecular Weight:
217.65
MDL number:
MFCD00012617
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
24900004
NACRES:
NA.32

product name

L-Tyrosine hydrochloride, ≥98% (TLC)

biological source

synthetic (organic)

Quality Level

200

Assay

≥98% (TLC)

form

powder

color

white to off-white

mp

239 °C (dec.) (lit.)

SMILES string

Cl[H].N[C@@H](Cc1ccc(O)cc1)C(O)=O

InChI

1S/C9H11NO3.ClH/c10-8(9(12)13)5-6-1-3-7(11)4-2-6;/h1-4,8,11H,5,10H2,(H,12,13);1H/t8-;/m0./s1

InChI key

JJWFIVDAMOFNPS-QRPNPIFTSA-N

Gene Information

human ... GRIN2C(2905)
mouse ... GRIN2C(14813)
rat ... GRIN2C(24411)

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Biochem/physiol Actions

Tyrosine is a nonessential amino acid found in mammal, fish and birds. It participates in protein modification, such as phosphorylation, nitrosation and sulfation. It is involved in immune response regulation and prevents the generation of inflammatory cytokines and superoxide. Tyrosine serves as a precursor for epinephrine, norepinephrine, dopamine, thyroid hormones and melanin biosynthesis. Tyrosine phosphorylation is associated with a number of cellular processes such as cell proliferation and migration, development of the embryo, cellular metabolism and transcription. Tyrosine phosphorylation also aids activation of the enzymatic function of a protein.

Other Notes

Amino acid precursor of dopamine and other catecholamines

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Resistance to Tyrosine Kinase Inhibitors, 37(1), 30-30 (2016)
Amino acids: metabolism, functions, and nutrition.
Wu G
Amino Acids, 37(1), 1-17 (2009)

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