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T1539

Sigma-Aldrich

(+)-α-Tocopherol

Type VI, from vegetable oil, liquid (≥0.88M based on potency, density and molecular wt.), BioReagent, suitable for insect cell culture, ≥1000 IU/g

Synonym(s):

2,5,7,8-Tetramethyl-2-(4′,8′,12′-trimethyltridecyl)-6-chromanol, 5,7,8-Trimethyltocol, D-α-Tocopherol, Vitamin E

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About This Item

Empirical Formula (Hill Notation):
C29H50O2
CAS Number:
59-02-9
Molecular Weight:
430.71
Beilstein:
4712525
EC Number:
200-412-2
MDL number:
MFCD00072045
UNSPSC Code:
12352205
eCl@ss:
34058016
PubChem Substance ID:
24899979
NACRES:
NA.75

biological source

vegetable oil

Quality Level

200

type

Type VI

product line

BioReagent

form

liquid (≥0.88M based on potency, density and molecular wt.)

potency

≥600 mg d-α-tocopherol per g

specific activity

≥1000 IU/g

mol wt

Mw 430.71 g/mol

concentration

≥600 mg/g

technique(s)

cell culture | insect: suitable

color

yellow-orange

refractive index

n20/D 1.505 (lit.)

bp

200-220 °C/0.1 mmHg (lit.)

solubility

chloroform: soluble 0.1 mL/mL, clear, faintly yellow to yellow

density

0.95 g/mL at 25 °C (lit.)

format

neat

storage temp.

2-8°C

SMILES string

CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCc2c(C)c(O)c(C)c(C)c2O1

InChI

1S/C29H50O2/c1-20(2)12-9-13-21(3)14-10-15-22(4)16-11-18-29(8)19-17-26-25(7)27(30)23(5)24(6)28(26)31-29/h20-22,30H,9-19H2,1-8H3/t21-,22-,29-/m1/s1

InChI key

GVJHHUAWPYXKBD-IEOSBIPESA-N

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Application

Use in insect cell culture applications as an antioxidant.

Other Notes

Mixed constitutional (α, β, γ, δ) isomers.

WGK

WGK 1

Flash Point(F)

230.0 °F

Flash Point(C)

110 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Laura L Baxter et al.
Nutrients, 4(6), 467-490 (2012-07-24)
Vitamin E isoforms are essential nutrients that are widely used as dietary supplements and therapeutic agents for a variety of diseases. However, their pharmacokinetic (PK) properties remain poorly characterized, and high dosage animal studies may provide further information on their
Karl Michaëlsson et al.
The American journal of clinical nutrition, 99(1), 107-114 (2013-11-15)
A reduction in the formation of free radicals and oxidative stress might reduce the rate of bone loss and muscle wasting. The objective was to determine whether α-tocopherol intake or serum concentrations are associated with fracture risk in older women
Jen-Hao Cheng et al.
European journal of medicinal chemistry, 46(4), 1222-1231 (2011-02-25)
In an effort to develop novel antioxidant as anticancer agents, a series of xanthones were prepared. In vitro screening, the synthetic xanthones revealed significant inhibitory effects on xanthine oxidase and ABTS radical-cation scavenging activity. The selective compounds 2 and 8
Ying Yang et al.
Food chemistry, 141(1), 473-481 (2013-06-19)
Vitamin E is an essential micronutrient for humans and animals due to its antioxidant and non-antioxidant biological activities. The α-tocopherol acetate form is often used in foods and other products due to its high biological activity and chemical stability. In
Y Loetscher et al.
Poultry science, 92(11), 2938-2948 (2013-10-19)
Prevention of lipid oxidation needs special attention because a high proportion of fatty acids in broiler meat are unsaturated. A feeding experiment was conducted to evaluate the antioxidant effect of dietary addition of rosemary, chokeberry pomace, rosehip, or nettle in
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