T0442
Anti-phospho-Tyk2 (pTyr1054/1055) antibody produced in rabbit
affinity isolated antibody, buffered aqueous glycerol solution
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous glycerol solution
mol wt
134 kDa
species reactivity
human
technique(s)
western blot: 1:1000
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... TYK2(7297)
Related Categories
General description
Tyk2 is a member of the Jak family of protein tyrosine kinases. It associates with and is activated by
receptors for many cytokines including IL-13, the IL-6 family, IL-10, and IFN-a and β. Following ligand binding,
Tyk2 is activated by phosphorylation of Tyr1054 and/or Tyr1055. Tyk2 is required for the tyrosine phosphoryla-
tion of Stat3 in the IFN-β signaling cascade.
receptors for many cytokines including IL-13, the IL-6 family, IL-10, and IFN-a and β. Following ligand binding,
Tyk2 is activated by phosphorylation of Tyr1054 and/or Tyr1055. Tyk2 is required for the tyrosine phosphoryla-
tion of Stat3 in the IFN-β signaling cascade.
Specificity
Detects human Tyk2 only when phosphorylated at Tyr1054/1055.
Immunogen
synthetic phospho-Tyr1054/1055 peptide corresponding to residues around Tyr1054/1055 of human Tyk2.
Physical form
Solution in 10 mM sodium HEPES, pH 7.5, containing 150 mM sodium chloride, 100 μg/ml bovine serum albumin and 50% glycerol
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Not finding the right product?
Try our Product Selector Tool.
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
含少量动物源组分生物产品
常规特殊物品
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service