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SRP6560

Sigma-Aldrich

Wnt-2 human

recombinant, expressed in E. coli, ≥90% (SDS-PAGE)

Synonym(s):

INT1L1, IRP, Int-1-like protein 1, Int-1-related protein

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About This Item

UNSPSC Code:
12352202
NACRES:
NA.32

biological source

human

recombinant

expressed in E. coli

Assay

≥90% (SDS-PAGE)

form

lyophilized

mol wt

39.9 kDa

packaging

pkg of 1 mg
pkg of 10 μg
pkg of 50 μg

UniProt accession no.

P09544

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... WNT2(7472)

Related Categories

Biochem/physiol Actions

Wnt gene family members, including Wnt-1 through Wnt-10, play a key role in regulating cellular growth and differentiation. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. Wnt family member-2 (Wnt-2) has a role in activating β-catenin. It has been shown to have a role in cardiogenesis. The protein is overexpressed in tumors and cancers.

Physical form

Lyophilized without additives.

Reconstitution

Reconstitute in sterile ddH2O to a concentration ≥ 100 μg/mL.

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

常规特殊物品

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Wnt2 complements Wnt/?-catenin signaling in colorectal cancer
Youn-Sang Jung
Oncotarget, 6(35), 37257-37268 (2015)
Wnt2 as a new therapeutic target in malignant pleural mesothelioma
Julien Mazieres
International Journal of Cancer. Journal International Du Cancer (2005)
Steven Hyman
Autism: The Science of Mental Health (2013)
Overexpression of Wnt-2 in colorectal cancers.
Park JK
Neoplasma, 56(2), 119-123 (2009)
Wnt signal transduction pathways
Yuko Komiya
Organogenesis, 4(2), 68-75 (2008)
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