SRP6318
Kininogen,HMW from human plasma
≥95% (SDS-PAGE)
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Alpha-2-thiol proteinase inhibitor, BDK, Fitzgerald factor, High molecular weight Kininogen, KNG, Kininogen-1 heavy chain, Kininogen-1 light chain, Low molecular weight growth-promoting, Lysyl-bradykinin, T-kinin Bradykinin, Williams-Fitzgerald-Flaujeac factor
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biological source
human plasma
Assay
≥95% (SDS-PAGE)
form
frozen liquid
mol wt
120 kDa
packaging
pkg of 100 μg
UniProt accession no.
shipped in
dry ice
storage temp.
−70°C
Gene Information
human ... KNG1(3827)
General description
HMW kininogen, synthesized by hepatocytes, is a multifunctional protein. It is the precursor protein of bradykinin. In addition it is a cofactor in the activation of factor XI, XII, and prekallikrein and a major extra-cellular cysteine proteinase inhibitor. Kininogens inhibit systemic proteases which are thought to have a part in various diseases such as cancer, muscular dystrophy and joint disease.
Physical form
Frozen in 10 mM Na acetate, pH 5.5 with 250 mM NaCI.
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
常规特殊物品
Certificates of Analysis (COA)
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