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Safety Information

SRP6318

Sigma-Aldrich

Kininogen,HMW from human plasma

≥95% (SDS-PAGE)

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Synonym(s):
Alpha-2-thiol proteinase inhibitor, BDK, Fitzgerald factor, High molecular weight Kininogen, KNG, Kininogen-1 heavy chain, Kininogen-1 light chain, Low molecular weight growth-promoting, Lysyl-bradykinin, T-kinin Bradykinin, Williams-Fitzgerald-Flaujeac factor
UNSPSC Code:
12352200
NACRES:
NA.32

biological source

human plasma

Assay

≥95% (SDS-PAGE)

form

frozen liquid

mol wt

120 kDa

packaging

pkg of 100 μg

UniProt accession no.

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... KNG1(3827)

General description

HMW kininogen, synthesized by hepatocytes, is a multifunctional protein. It is the precursor protein of bradykinin. In addition it is a cofactor in the activation of factor XI, XII, and prekallikrein and a major extra-cellular cysteine proteinase inhibitor. Kininogens inhibit systemic proteases which are thought to have a part in various diseases such as cancer, muscular dystrophy and joint disease.

Physical form

Frozen in 10 mM Na acetate, pH 5.5 with 250 mM NaCI.

Pictograms

Health hazardExclamation mark

Signal Word

Danger

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

常规特殊物品

Certificates of Analysis (COA)

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