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SRP6299

Sigma-Aldrich

CD71/TFRC/TFR human

recombinant, expressed in HEK 293 cells, ≥92% (SDS-PAGE)

Synonym(s):

T9, TfR1, Trfr, p90, sTfR

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About This Item

UNSPSC Code:
12352200
NACRES:
NA.77

biological source

human

recombinant

expressed in HEK 293 cells

tag

6-His tagged (N-terminus)

Assay

≥92% (SDS-PAGE)

form

lyophilized

mol wt

calculated mol wt 76 kDa
observed mol wt 80-85 kDa (DTT-reduced. Protein migrates due to glycosylation. Cys 89 is the predicted N-terminus.)

packaging

pkg of 10 and 50 μg
pkg of 10 μg

UniProt accession no.

P02786

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... TFRC(7037)

General description

CD antigen CD71 is also known as Transferrin receptor protein 1, TfR, sTfR, p90, TfR1, Trfr, which belongs to the peptidase M28 family and M28B subfamily. CD71 /TFR contains one PA (protease associated) domain. CD71 / TfR1 is required for iron delivery from transferrin to cells. CD71 is a potential new target in cases of human leukemia & lymphoma. CD71 /TFRC / TfR has been shown to interact with GABARAP and HFE.

Physical form

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Generally 5-8% Mannitol or trehalose is added as a protectant before lyophilization.

Reconstitution

Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 μg/mL. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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