SRP3246
IP-10 from rat
recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture
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Synonym(s):
CXCL10, crg-2, g-Interferon Inducible Protein 10
UNSPSC Code:
12352200
NACRES:
NA.32
Recommended Products
biological source
rat
recombinant
expressed in E. coli
Assay
≥98% (HPLC)
≥98% (SDS-PAGE)
form
lyophilized
mol wt
8.6 kDa
packaging
pkg of 25 μg
technique(s)
cell culture | mammalian: suitable
impurities
<0.2 EU/μg endotoxin, tested
color
off-white to yellow
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
Gene Information
rat ... CXCL10(245920)
General description
IP-10 is a CXC chemokine that signals through the CXCR3 receptor. IP-10 selectively chemoattracts Th1 lymphocytes and monocytes, and inhibits cytokine-stimulated hematopoietic progenitor cell proliferation. Additionally, it is angiostatic and mitogenic for vascular smooth muscle cells. Recombinant rat IP-10 is an 8.6 kDa protein containing 77 amino acid residues, including the four conserved cysteine residues present in CXC chemokines.
Biochem/physiol Actions
IP-10 is a CXC chemokine that signals through the CXCR3 receptor. Recombinant rat IP-10 is an 8.6 kDa protein containing 77 amino acid residues, including the four conserved cysteine residues present in CXC chemokines.
Sequence
IPLARTVRCT CIDFHEQPLR PRAIGKLEII PASLSCPHVE IIATMKKNNE KRCLNPESEA IKSLLKAVSQ RRSKRAP
Physical form
Lyophilized with no additives.
Reconstitution
Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
WGK
WGK 1
Regulatory Information
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