SRP0476
SMARCA2 (1375-1511) human
recombinant, expressed in E. coli, ≥90% (SDS-PAGE)
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Synonym(s):
BRM, SNF2, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2, SWI2, Sth1p
UNSPSC Code:
12352202
NACRES:
NA.32
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biological source
human
recombinant
expressed in E. coli
Assay
≥90% (SDS-PAGE)
form
aqueous solution
mol wt
16.9 kDa
packaging
pkg of 100 μg
NCBI accession no.
UniProt accession no.
shipped in
dry ice
storage temp.
−70°C
Gene Information
human ... SMARCA2(6595)
General description
Human Bromodomain SMARCA2 or BRM (GenBank Accession No. NM_003070) amino-acids 1375 – 1511 with N-terminal HIS-tag, MW = 16.9 kDa, expressed in an E. coli expression system.
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
常规特殊物品
Certificates of Analysis (COA)
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A Hunter Shain et al.
Proceedings of the National Academy of Sciences of the United States of America, 109(5), E252-E259 (2012-01-12)
Defining the molecular genetic alterations underlying pancreatic cancer may provide unique therapeutic insight for this deadly disease. Toward this goal, we report here an integrative DNA microarray and sequencing-based analysis of pancreatic cancer genomes. Notable among the alterations newly identified
G Liu et al.
Oncogene, 30(29), 3295-3304 (2011-04-12)
SWI/SNF (SWItch/sucrose non-fermentable) complexes are ATP-dependent chromatin remodeling enzymes critically involved in the regulation of multiple functions, including gene expression, differentiation, development, DNA repair, cell adhesion and cell cycle control. BRM, a key SWI/SNF complex subunit, is silenced in 15-20%
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