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Merck
CN

SML4045

Salvianolic acid A

≥98% (HPLC)

Synonym(s):

(αR)-α-[[(2E)-3-[2-[(1E)-2-(3,4-Dihydroxyphenyl)ethenyl]-3,4-dihydroxyphenyl]-1-oxo-2-propen-1-yl]oxy]-3,4-dihydroxybenzenepropanoic acid, (+)-Salvianolic acid A, Dan phenolic acid A

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About This Item

Empirical Formula (Hill Notation):
C26H22O10
CAS Number:
96574-01-5
Molecular Weight:
494.45
UNSPSC Code:
41116107
MDL number:
MFCD08458447
NACRES:
NA.21

Key Documents

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Product Name

Salvianolic acid A, ≥98% (HPLC)

SMILES string

O([C@H](Cc3cc(c(cc3)O)O)C(=O)O)C(=O)\C=C\c1c(c(c(cc1)O)O)\C=C\c2cc(c(cc2)O)O

InChI key

YMGFTDKNIWPMGF-UCPJVGPRSA-N

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

-10 to -25°C

Quality Level

100

Related Categories

Biochem/physiol Actions

Cell protective antioxidant isolated from Salvia.Salvianolic acid A is cell protective antioxidant originally isolated from Salvia. It has been found to attenuate PDGF-induced ROS formation in hepatic stellate cells and protected against isoproterenol-induced myocardial damage in rats.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
0000360767
0000360767

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Fan Tang et al.
Antioxidants (Basel, Switzerland), 12(4) (2023-04-28)
The vast majority of drug-induced liver injury is mainly attributed to acetaminophen (APAP) overdose. Salvianolic acid A (Sal A), a powerful water-soluble compound obtained from Salvia miltiorrhiza, has been confirmed to exert hepatoprotective effects. However, the beneficial effects and the
Xiaxia Fan et al.
Journal of ethnopharmacology, 308, 116219-116219 (2023-02-10)
Salvianolic acid A (SAA) is the main active component of the classic anti-atherosclerotic drug Salvia miltiorrhiza Bunge. Inflammation-induced infiltration of monocyte/macrophages into the vascular wall is the initiating step in atherogenesis, and targeted blocking of this step may provide a
Ji Zhu et al.
Frontiers in pharmacology, 13, 1009229-1009229 (2022-11-26)
Rescuing endothelial cells from pyroptotic cell death emerges as a potential therapeutic strategy to combat diabetic atherosclerosis. Salvianolic acid A (SAA) is a major water-soluble phenolic acid in the Salvia miltiorrhiza Bunge, which has been used in traditional Chinese medicine

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