All Photos(1)
Synonym(s):
(2S,5R)-7-Oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide monosodium salt, AVE1330A sodium salt, NXL-104 sodium salt, Sulfuric acid mono[(1R,2S,5R)-2-(aminocarbonyl)-7-oxo-1,6-diazabicyclo[3.2.1]oct-6-yl] ester sodium salt
Empirical Formula (Hill Notation):
C7H10N3NaO6S
CAS Number:
Molecular Weight:
287.23
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.21
Recommended Products
Quality Level
Assay
≥98% (HPLC)
form
powder
storage condition
desiccated
color
white to beige
solubility
H2O: 2 mg/mL, clear
storage temp.
-10 to -25°C
Biochem/physiol Actions
Avibactam is a reversible non-β-lactam β-lactamase inhibitor with IC50 values of 5 nM for CTX-M-15, 8nM for TEM-1, and 80 nM for P99 β-lactamase enzymes.
Caution
Hygroscopic
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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Certificates of Analysis (COA)
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Find documentation for the products that you have recently purchased in the Document Library.
Efficacies of ceftazidime-avibactam and ceftazidime against Pseudomonas aeruginosa in a murine lung infection model
Antimicrobial Agents and Chemotherapy, 58(3), 1365-1371 (2014)
Avibactam is a covalent, reversible, non-?-lactam ?-lactamase inhibitor
Proceedings of the National Academy of Sciences of the USA, 109(29), 11663-11668 (2012)
Carbapenemase Inhibitors: Updates on Developments in 2021
Journal of clinical medicine research, 14(7), 251-259 (2022)
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