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Merck
CN

SML3206

Ginsenoside Rg5

≥98% (HPLC), Anti-inflammatory, powder

Synonym(s):

(3β, 12β,20E)-12-Hydroxydammara-20(22),24-dien-3-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside

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About This Item

Empirical Formula (Hill Notation):
C42H70O12
CAS Number:
Molecular Weight:
767.00
UNSPSC Code:
12352107
NACRES:
NA.77
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Product Name

Ginsenoside Rg5, ≥98% (HPLC)

SMILES string

O1[C@H]([C@@H]([C@H]([C@@H]([C@H]1CO)O)O)O)O[C@H]2[C@@H](O[C@@H]([C@H]([C@@H]2O)O)CO)O[C@@H]3C([C@H]4[C@@]([C@@H]5[C@]([C@]6([C@H]([C@@H](C5)O)[C@H](CC6)\C(=C\CC=C(C)C)\C)C)(CC4)C)(CC3)C)(C)C

InChI

1S/C42H70O12/c1-21(2)10-9-11-22(3)23-12-16-42(8)30(23)24(45)18-28-40(6)15-14-29(39(4,5)27(40)13-17-41(28,42)7)53-38-36(34(49)32(47)26(20-44)52-38)54-37-35(50)33(48)31(46)25(19-43)51-37/h10-11,23-38,43-50H,9,12-20H2,1-8H3/b22-11+/t23-,24-,25-,26-,27+,28-,2

InChI key

NJUXRKMKOFXMRX-RNCAKNGISA-N

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

−20°C

Quality Level

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pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Young-Lai Cho et al.
The Journal of biological chemistry, 290(1), 467-477 (2014-11-14)
Ginsenoside Rg5 is a compound newly synthesized during the steaming process of ginseng; however, its biological activity has not been elucidated with regard to endothelial function. We found that Rg5 stimulated in vitro angiogenesis of human endothelial cells, consistent with
Yange Wei et al.
Journal of agricultural and food chemistry, 68(18), 5107-5117 (2020-04-21)
In this study, we aimed to investigate the influence of ginsenoside Rg5 (Rg5) on gut microbiota in diabetic db/db mice. Our data indicated that Rg5 not only improved the symptoms of hyperglycemia, repaired intestinal barrier function, and relieved metabolic endotoxemia-related
Yu Young Lee et al.
International journal of molecular sciences, 14(5), 9820-9833 (2013-05-24)
Microglia are resident immune cells in the central nervous system. They play a role in normal brain development and neuronal recovery. However, overactivation of microglia causes neuronal death, which is associated with neurodegenerative diseases, such as Parkinson's disease and Alzheimer's

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