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SML3128

Sigma-Aldrich

HU-308

≥98% (HPLC)

Synonym(s):

(1S,4S,5S)-4-[4-(1,1-Dimethylheptyl)-2,6-dimethoxyphenyl]-6,6-dimethylbicyclo[3.1.1]hept-2-ene-2-methanol, HU308

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About This Item

Empirical Formula (Hill Notation):
C27H42O3
CAS Number:
256934-39-1
Molecular Weight:
414.62
MDL number:
MFCD23102377
UNSPSC Code:
12352200
NACRES:
NA.77

Quality Level

100

Assay

≥98% (HPLC)

optical activity

[α]/D 180.0 to 130.0°, c = 0.5 in chloroform-d

storage condition

desiccated

color

white to dark beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

−20°C

SMILES string

CCCCCCC(C)(C1=CC(OC)=C(C(OC)=C1)[C@]2(C=C([C@@H]3C(C)([C@H]2C3)C)CO)[H])C

InChI

1S/C27H42O3/c1-8-9-10-11-12-26(2,3)19-14-23(29-6)25(24(15-19)30-7)20-13-18(17-28)21-16-22(20)27(21,4)5/h13-15,20-22,28H,8-12,16-17H2,1-7H3/t20-,21+,22-/m0/s1

InChI key

CFMRIVODIXTERW-BDTNDASRSA-N

Biochem/physiol Actions

HU-308 is a potent, selective agonist of the cannabinoid receptor CB2. The Ki values for CB2 vs. CB1 are 22.7nM and >10 mM, respectively. HU-308 has anti-inflammatory and neuroprotective properties, and reduces liver damage in a hepatic ischemia/reperfusion injury model.

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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