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SML2510

Flubendazol

Name: Flubendazol
Brand: SIGMA

Synonym(s):

Flubendazol, Flubendazole, Flumoxanal, Methyl [5-(4-fluorobenzoyl)-1H-benzimidazol-2-yl]carbamate

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About This Item

Empirical Formula (Hill Notation):

C₁₆H₁₂FN₃O₃

CAS Number:

31430-15-6

Molecular Weight:

313.28

MDL number:

MFCD00871999

UNSPSC Code:

12352200

NACRES:

NA.77

form

powder

storage temp.

2-8°C

SMILES string

COC(=O)Nc1nc2cc(ccc2[nH]1)C(=O)c3ccc(F)cc3

InChI

1S/C16H12FN3O3/c1-23-16(22)20-15-18-12-7-4-10(8-13(12)19-15)14(21)9-2-5-11(17)6-3-9/h2-8H,1H3,(H2,18,19,20,22)

InChI key

CPEUVMUXAHMANV-UHFFFAOYSA-N

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Biochem/physiol Actions

Flubendazole, an antithelmintic, has been widely used in treating intestinal parasites. Additionally, Flubendazole has been reported to exert anticancer activities.

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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Flubendazole elicits anti-cancer effects via targeting EVA1A-modulated autophagy and apoptosis in Triple-negative Breast Cancer.

Yongqi Zhen et al.

Theranostics, 10(18), 8080-8097 (2020-07-30)

Background: Triple-negative breast cancer (TNBC) is one of the most prevalent neoplastic diseases worldwide, but efficacious treatments for this pathological condition are still challenging. The lack of an effective targeted therapy also leads to a poor prognosis for patients affected

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