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SML2429

Sigma-Aldrich

3,3′,4-Tri-O-methylellagic acid

≥95% (HPLC)

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Synonym(s):
3,3’,4-Tri-O-methylellagic acid, 2,3,8-Tri-O-methylellagic acid, 3-hydroxy-2,7,8-trimethoxy- [1]Benzopyrano[5,4,3-cde][1]benzopyran-5,10-dione, Nasutin B
Empirical Formula (Hill Notation):
C17H12O8
CAS Number:
Molecular Weight:
344.27
MDL number:
UNSPSC Code:
12352106
NACRES:
NA.77

Assay

≥95% (HPLC)

form

solid

storage temp.

−20°C

InChI

1S/C17H12O8/c1-21-9-5-7-11-10-6(16(19)25-15(11)13(9)23-3)4-8(18)12(22-2)14(10)24-17(7)20/h4-5,18H,1-3H3

InChI key

LXEQIOGTMDLLEC-UHFFFAOYSA-N

General description

3,3′,4-Tri-O-methylellagic acid is the methylated analogue of Ellagic acid. 3,3′,4-Tri-O-methylellagic acid was initially isolated from the rhizomes of Euphorbia acaulis.
3,3′,4-Tri-O-methylellagic acid was found to have anti-diabetic properties in mice models treated with Alloxan. Furthermore, 3,3′,4-Tri-O-methylellagic acid was reported to possess anti-bacterial activity against several bacterial strains including, Klebsiella pneumoniae, Enterobacter aerogenes and Staphylococcus aureus.

Other Notes

Solubility: 5mg/ml in DMSO (requires heat), in case of precipitation reheat solution.

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Igor K Voukeng et al.
BMC complementary and alternative medicine, 17(1), 28-28 (2017-01-08)
Elaeophorbia drupifera (Thonn.) Stapf. (Euphorbiaceae) is used in Cameroonian folk medicine to treat several ailments including bacterial-related diseases such as skin infections. In this study, the methanol extract from the leaves (EDL), fractions (EDLa-d), sub-fractions EDLc1-7 and EDLc31-35 as well
Philip F Uzor et al.
EXCLI journal, 15, 290-296 (2016-06-15)
The root of Combretum dolichopetalum (Combreatacea) is used in ethnomedicine for the management of diabetes mellitus. Though some compounds have been isolated from it, the antidiabetic principles have not been identified. The present study was designed to evaluate the chemical

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